IL-6 ELISA 试剂盒
Quick Overview for IL-6 ELISA 试剂盒 (ABIN2042557)
抗原
See all IL-6 (IL6) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
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最低检测浓度
- 4.9 pg/mL
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品牌
- BioAssay™
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Analytical Method
- Quantitative
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交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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灵敏度
- < 0.3 pg/mL
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组件
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A: Microtiter Strip 1x96wells pre-coated with anti-IL-6, Human
B: Standard, Recombinant IL-6 Human, 10 ng, 2x1 vial Lyophilized
C: Anti-human IL-6 (Biotin), 1x130 µL
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板类型
- Pre-coated
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实验流程
- Sandwich ELISA quantitative detection kit for Human IL-6 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).The human interferon-beta 2 gene (IFNB2) product is identical to that for the B-cell stimulation factor-2 (BSF-2), the hybridoma growth factor (HGF) ("interleukin-6"), and the hepatocyte stimulating factor (HSF). Proteins derived from this gene mediate the plasma protein response to tissue injury (acute-phase response) and regulate the growth and differentiation of both B and T cells.1 Interleukin-6 (IL6) has come to be regarded as a potential osteoporotic factor because it has stimulatory effects on cells of the osteoclast lineage, and, thus, may play a role in the pathogenesis of bone loss associated with estrogen deficiency.2 IL-6 has many roles essential to the regulation of the immune response, hematopoiesis, and bone resorption.3 It is involved not only in the hepatic acute phase response but also in adipose tissue metabolism, lipoprotein lipase activity, and hepatic triglyceride secretion.4 Overproduction of IL-6, a proinflammatory cytokine, is associated with a spectrum of age-related conditions including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes, certain cancers, periodontal disease, frailty, and functional decline.5 BSF-2 is a novel interleukin consisting of 184 amino acids.6 The standard product used in this kit is recombinant human IL-6, consisting of 184 amino acids with the molecular mass of 20.3kD.
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限制
- 仅限研究用
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储存条件
- 4 °C/-20 °C
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- IL-6 (IL6) (Interleukin 6 (IL6))
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别名
- IL-6
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途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
抗原 See all IL-6 (IL6) ELISA试剂盒
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