HAP1 抗体
(Huntingtin Associated Protein 1 (HAP1))
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| HAP1 抗体 (Internal Region) | 人 | 山羊 Polyclonal |
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| HAP1 抗体 (AA 328-580) | 人 | 兔 Polyclonal |
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| HAP1 抗体 (AA 1-671) | 人 | 兔 Polyclonal |
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| HAP1 抗体 (AA 1-671) | 人 | 小鼠 Polyclonal |
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| HAP1 抗体 (C-Term) | 小鼠, 大鼠 | 山羊 Polyclonal |
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| HAP1 抗体 (AA 1-671) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| HAP1 抗体 (AA 132-328) | 小鼠 | 兔 Polyclonal |
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| HAP1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| HAP1 抗体 (AA 310-360) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| HAP1 抗体 (AA 328-580) (HRP) | 人 | 兔 Polyclonal |
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| HAP1 抗体 (AA 328-580) (FITC) | 人 | 兔 Polyclonal |
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| HAP1 抗体 (AA 328-580) (Biotin) | 人 | 兔 Polyclonal |
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| HAP1 抗体 | 人 | 兔 Polyclonal |
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| HAP1 抗体 | 小鼠 | 兔 Polyclonal |
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| HAP1 抗体 | 大鼠 | 兔 Polyclonal |
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| HAP1 抗体 (AA 160-381) | 人 | 兔 Polyclonal |
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| HAP1 抗体 | 大鼠 | 小鼠 Monoclonal |
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| HAP1 抗体 (AA 349-584) | 大鼠 | 兔 Polyclonal |
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| HAP1 抗体 (Center) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| HAP1 抗体 (AA 1-671) (APC) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 328-580
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-671
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-671
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 小鼠, 大鼠
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-671
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 132-328
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 310-360
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 328-580
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 328-580
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 328-580
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 160-381
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 349-584
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- EIA (Enzyme Immunoassay: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 1-671
Latest Publications for our HAP1 抗体
: "DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 7, pp. E1224-E1233, (2017) (PubMed).
: "Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7887-96, (2015) (PubMed).
: "Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 8, pp. 2004-16, (2014) (PubMed).
: "Huntingtin mediates dendritic transport of ?-actin mRNA in rat neurons." in: Scientific reports, Vol. 1, pp. 140, (2012) (PubMed).
: "Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies." in: Cellular and molecular life sciences : CMLS, Vol. 63, Issue 22, pp. 2642-60, (2006) (PubMed).
: "Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 22, pp. 6019-30, (2006) (PubMed).
: "Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis." in: Human molecular genetics, Vol. 15, Issue 15, pp. 2298-312, (2006) (PubMed).
: "Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules." in: Cell, Vol. 118, Issue 1, pp. 127-38, (2004) (PubMed).
: "Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 51, Issue 6, pp. 841-52, (2003) (PubMed).
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
: "Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7887-96, (2015) (PubMed).
: "Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 8, pp. 2004-16, (2014) (PubMed).
: "Huntingtin mediates dendritic transport of ?-actin mRNA in rat neurons." in: Scientific reports, Vol. 1, pp. 140, (2012) (PubMed).
: "Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies." in: Cellular and molecular life sciences : CMLS, Vol. 63, Issue 22, pp. 2642-60, (2006) (PubMed).
: "Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 22, pp. 6019-30, (2006) (PubMed).
: "Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis." in: Human molecular genetics, Vol. 15, Issue 15, pp. 2298-312, (2006) (PubMed).
: "Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules." in: Cell, Vol. 118, Issue 1, pp. 127-38, (2004) (PubMed).
: "Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 51, Issue 6, pp. 841-52, (2003) (PubMed).
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
Aliases for HAP1 抗体
huntingtin associated protein 1 (HAP1) 抗体huntingtin-associated protein 1 (Hap1) 抗体
HAP-1 抗体
HAP1-A 抗体
HAP1-B 抗体
HAP2 抗体
hHLP1 抗体
HIP5 抗体
HLP 抗体
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