HACE1 抗体
(HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB (By similarity).
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HACE1
适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马, 猴, Pig
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Aliases for HACE1 抗体
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) 抗体HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (hace1) 抗体
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 L homeolog (hace1.L) 抗体
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (Hace1) 抗体
1700042J16Rik 抗体
A730034A22Rik 抗体
BC025474 抗体
HACE1 抗体
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