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HACE1 抗体 (AA 333-442) (HRP)

HACE1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7151028
发货至: 中国
  • 抗原 See all HACE1 抗体
    HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 333-442
    适用
    • 33
    • 16
    • 14
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 22
    • 12
    克隆类型
    • 23
    • 11
    多克隆
    标记
    • 20
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HACE1 antibody is conjugated to HRP
    应用范围
    • 19
    • 18
    • 10
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human E3 ubiquitin-protein ligase HACE1 protein (333-442AA)
    亚型
    IgG
    Top Product
    Discover our top product HACE1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))
    别名
    HACE1 (HACE1 产品)
    别名
    HACE1 antibody, 1700042J16Rik antibody, A730034A22Rik antibody, BC025474 antibody, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 antibody, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 L homeolog antibody, HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 antibody, HACE1 antibody, hace1 antibody, hace1.L antibody, Hace1 antibody
    背景

    Background: E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.

    Aliases: HACE1 antibody, KIAA1320E3 ubiquitin-protein ligase HACE1 antibody, EC 2.3.2.26 antibody, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 antibody, HECT-type E3 ubiquitin transferase HACE1 antibody

    UniProt
    Q8IYU2
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