HAP1 抗体
Our Local Distributor
北京 101111
Quick Overview for HAP1 抗体 (ABIN7228840)
抗原
See all HAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-HAP1 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of HAP1 protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human HAP1 protein
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- HAP1 (Huntingtin Associated Protein 1 (HAP1))
-
别名
- HAP1
-
背景
- Huntingtin-associated protein 1, HAP-1, Neuroan 1HAP1 (Huntingtin Associated Protein 1) is a Protein Coding gene. Diseases associated with HAP1 include Huntington Disease and Spinocerebellar Ataxia 17. Among its related pathways are GABAergic synapse and fMLP Pathway. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. HAP1 encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport.
-
分子量
- 73kD
-
基因ID
- 9001
-
UniProt
- P54257
-
途径
- Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
抗原
-