HAP1 抗体
(Huntingtin Associated Protein 1 (HAP1))
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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25 results
Verified
HAP1
适用: 人
WB, IHC, ELISA
宿主: 山羊
Polyclonal
unconjugated
HAP1
适用: 人, 小鼠, 大鼠
WB, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our HAP1 抗体
: "DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 7, pp. E1224-E1233, (2017) (PubMed).: "Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7887-96, (2015) (PubMed).
: "Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 8, pp. 2004-16, (2014) (PubMed).
: "Huntingtin mediates dendritic transport of ?-actin mRNA in rat neurons." in: Scientific reports, Vol. 1, pp. 140, (2012) (PubMed).
: "Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies." in: Cellular and molecular life sciences : CMLS, Vol. 63, Issue 22, pp. 2642-60, (2006) (PubMed).
: "Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 22, pp. 6019-30, (2006) (PubMed).
: "Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis." in: Human molecular genetics, Vol. 15, Issue 15, pp. 2298-312, (2006) (PubMed).
: "Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules." in: Cell, Vol. 118, Issue 1, pp. 127-38, (2004) (PubMed).
: "Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 51, Issue 6, pp. 841-52, (2003) (PubMed).
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
Aliases for HAP1 抗体
huntingtin associated protein 1 (HAP1) 抗体huntingtin-associated protein 1 (Hap1) 抗体
HAP-1 抗体
HAP1-A 抗体
HAP1-B 抗体
HAP2 抗体
hHLP1 抗体
HIP5 抗体
HLP 抗体
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