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HAP1 抗体

(Huntingtin Associated Protein 1 (HAP1))
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

25 results

Verified HAP1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN334416
 
HAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5013715
 
HAP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7155933
 
Verified HAP1 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN190785
 
HAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN522442
 
HAP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN948757
 
HAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1868320
 
HAP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5013714
 
HAP1 适用: 大鼠 WB, IHC, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated
产品编号 ABIN363256
 
HAP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499942
 
HAP1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7155936
 
HAP1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7155935
 
HAP1 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7155934
 
HAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7640405
 
HAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7640406
 
HAP1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7640408
 
HAP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7640407
 
HAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990748
 
HAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2605309
 
HAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7267795
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • ELISA
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Enzyme Immunoassay (EIA)
    • Flow Cytometry (FACS)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Rat
    • Mouse
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 1B6
  • 抗原表位
    • AA 1-671
    • AA 328-580
    • AA 132-328
    • AA 160-381
    • AA 349-584
    • AA 1-240
    • AA 310-360
    • C-Term
    • Center
    • Internal Region
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
  • 抗体亚型
    • IgG
    • IgG1
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Biomatik
    • Cloud-Clone
    • Abbexa
    • Acris
    • Boster Bio
    • Covalab

Latest Publications for our HAP1 抗体

Xiang, Yang, Xin, Gaertig, Reeves, Li, Li: "DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 7, pp. E1224-E1233, (2017) (PubMed).

Corradini, Burgers, Plank, Heck, Scholten: "Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7887-96, (2015) (PubMed).

Corradini, Vallur, Raaijmakers, Feil, Feil, Heck, Scholten: "Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 8, pp. 2004-16, (2014) (PubMed).

Ma, Savas, Yu, Culver, Chao, Tanese: "Huntingtin mediates dendritic transport of ?-actin mRNA in rat neurons." in: Scientific reports, Vol. 1, pp. 140, (2012) (PubMed).

Borrell-Pagès, Zala, Humbert, Saudou: "Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies." in: Cellular and molecular life sciences : CMLS, Vol. 63, Issue 22, pp. 2642-60, (2006) (PubMed).

Rong, McGuire, Fang, Sheng, Shin, Li, Li: "Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 22, pp. 6019-30, (2006) (PubMed).

Takeshita, Fujinaga, Zhao, Yanai, Shinoda: "Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis." in: Human molecular genetics, Vol. 15, Issue 15, pp. 2298-312, (2006) (PubMed).

Gauthier, Charrin, Borrell-Pagès, Dompierre, Rangone, Cordelières, De Mey, MacDonald, Lessmann, Humbert, Saudou: "Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules." in: Cell, Vol. 118, Issue 1, pp. 127-38, (2004) (PubMed).

Gutekunst, Torre, Sheng, Yi, Coleman, Riedel, Bujo: "Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 51, Issue 6, pp. 841-52, (2003) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Aliases for HAP1 抗体

huntingtin associated protein 1 (HAP1) 抗体
huntingtin-associated protein 1 (Hap1) 抗体
HAP-1 抗体
HAP1-A 抗体
HAP1-B 抗体
HAP2 抗体
hHLP1 抗体
HIP5 抗体
HLP 抗体
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