GCH1 抗体
(GTP Cyclohydrolase 1 (GCH1))
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described\; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008].
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51 results
Verified
GCH1
适用: 人
ELISA, IHC
宿主: 山羊
Polyclonal
unconjugated
GCH1
适用: 小鼠
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
1 image
GCH1
适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Bat, 小鸡, Hamster, 猴, 非洲爪蟾
WB
宿主: 兔
Polyclonal
unconjugated
1 image
GCH1
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
GCH1
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
GCH1
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 594
GCH1
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 488
GCH1
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 555
GCH1
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 350
GCH1
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 647
Latest Publications for our GCH1 抗体
: "Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats." in: Vascular pharmacology, Vol. 71, pp. 181-91, (2015) (PubMed).: "Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd²?-induced apoptosis." in: Free radical biology & medicine, Vol. 74, pp. 188-99, (2014) (PubMed).
: "Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II." in: The Journal of biological chemistry, Vol. 289, Issue 40, pp. 27540-50, (2014) (PubMed).
: "Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages." in: International journal of cancer. Journal international du cancer, Vol. 132, Issue 3, pp. 591-604, (2012) (PubMed).
: "Vascular dysfunction in streptozotocin-induced experimental diabetes strictly depends on insulin deficiency." in: Journal of vascular research, Vol. 48, Issue 4, pp. 275-84, (2011) (PubMed).
: "Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 301, Issue 3, pp. L334-45, (2011) (PubMed).
: "Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy." in: Diabetes, Vol. 60, Issue 10, pp. 2608-16, (2011) (PubMed).
: "Differential effects of heart rate reduction with ivabradine in two models of endothelial dysfunction and oxidative stress." in: Basic research in cardiology, Vol. 106, Issue 6, pp. 1147-58, (2011) (PubMed).
: "Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus." in: Atherosclerosis, Vol. 198, Issue 1, pp. 65-76, (2008) (PubMed).
: "Role of angiotensin II on dihydrofolate reductase, GTP-cyclohydrolase 1 and nitric oxide synthase expressions in renal ischemia-reperfusion." in: American journal of nephrology, Vol. 28, Issue 4, pp. 692-700, (2008) (PubMed).
Aliases for GCH1 抗体
GTP cyclohydrolase 1 (GCH1) 抗体GTP cyclohydrolase 1 (Gch1) 抗体
GTP cyclohydrolase 1 (gch1) 抗体
GTP cyclohydrolase 1 (Weevi_1190) 抗体
GTP cyclohydrolase 1 (Halhy_0838) 抗体
GTP cyclohydrolase 1 (Sinme_1220) 抗体
GTP cyclohydrolase 1 (Sphch_1077) 抗体
GTP cyclohydrolase 1-like (LOC100136794) 抗体
DYT5 抗体
DYT5a 抗体
DYT14 抗体
GCH 抗体
Gch 抗体
gch1a 抗体
GTP-CH 抗体
GTP-CH-1 抗体
GTPCH 抗体
GTPCH1 抗体
HPABH4B 抗体
MGC89622 抗体
wu:fc16b10 抗体
zgc:195269 抗体
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