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GCLC 抗体

(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010].
GCLC 抗体  (AA 528-637) GCLC 抗体  (AA 528-637) GCLC 抗体 (AA 528-637) (ABIN561050)

GCLC 适用: 人 IF, ELISA, WB 宿主: 小鼠 Monoclonal 3H1 unconjugated

GCLC 抗体  (N-Term) GCLC 抗体  (N-Term) GCLC 抗体 (N-Term) (ABIN2774078)

GCLC 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated

GCLC 抗体  (AA 1-30) GCLC 抗体  (AA 1-30) GCLC 抗体 (AA 1-30) (ABIN3031076)

GCLC 适用: 人 FACS, IF, IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated

GCLC 抗体 by 适用

Find GCLC 抗体 for a variety of species such as anti-Human GCLC, anti-Rat GCLC, anti-Mouse GCLC. The species listed below are among those available. Click on a link to go to the corresponding products.

GCLC 抗体 by 应用范围

Find GCLC 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

GCLC 抗体 by 抗体来源

Find GCLC 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

GCLC 抗体 by 抗原表位

Find GCLC 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

GCLC 抗体 by 克隆形成能力

Find available monoclonal or polyclonal GCLC 抗体. Click on a link to go to the corresponding products.

GCLC 抗体 by 克隆

Find GCLC 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

GCLC 抗体 by 标记

Find GCLC 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular GCLC 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application IHC, WB
Validations
  • (1)
  • (5)
Cat. No. ABIN2774078
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF, IHC, ELISA, WB
Validations
  • (7)
Cat. No. ABIN3031076
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Rat
Application IHC (p), WB
Validations
  • (2)
  • (4)
Cat. No. ABIN3042420
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Pig, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (2)
  • (3)
Cat. No. ABIN6261919
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ICC, IHC, WB
Validations
  • (4)
Cat. No. ABIN1858972
Quantity 100 μL
Datasheet Datasheet

Application IHC, WB
Validations
  • (2)
  • (3)
Cat. No. ABIN2785780
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application EIA, FACS, IF, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN952477
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN3031077
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7252117
Quantity 200 μL
Datasheet Datasheet

Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN6747154
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, WB
Validations
  • (2)
Cat. No. ABIN1858974
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7186811
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7153998
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS, IF, IHC (p), WB
Validations
  • (1)
Cat. No. ABIN655884
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN928732
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our GCLC 抗体

Khaliq, Jing, Ke, Ke-Li, Peng-Peng, Cui, Wei-Wei, Zhixin, Hua-Zhen, Hui, Ju-Ming, Ke-Mei: "Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks." in: Biological trace element research, Vol. 186, Issue 1, pp. 226-237, (2018) (PubMed).

Petersen, Saba, Sayin, Papagiannakopoulos, Schmidt, Merrill, Orlicky, Shearn: "Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice." in: PLoS ONE, Vol. 13, Issue 5, pp. e0198139, (2018) (PubMed).

Zou, Wang, Peng, Wei: "Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5987183, (2017) (PubMed).

Li, Sun, Liu, Zhao, Shao: "Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 102, pp. 93-101, (2017) (PubMed).

Ni, Wang, Qiu, Pang, Song, Guo: "Bone marrow mesenchymal stem cells protect against bleomycin-induced pulmonary fibrosis in rat by activating Nrf2 signaling." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7752-61, (2016) (PubMed).

Jin, Li, Zhang, Wu, Feng, Zhang, Shen: "Electroacupuncture alleviates cerebral ischemia and reperfusion injury via modulation of the ERK1/2 signaling pathway." in: Neural regeneration research, Vol. 11, Issue 7, pp. 1090-8, (2016) (PubMed).

Sugiyama, Ebinuma, Nakamoto, Sakasegawa, Murakami, Chu, Usui, Ishibashi, Wakayama, Taniki, Murata, Saito, Fukasawa, Saito, Yamagishi, Wakita, Takaku, Hibi, Saito, Kanai: "Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus." in: PLoS ONE, Vol. 9, Issue 4, pp. e94460, (2014) (PubMed).

Venè, Cardinali, Arena, Ferrari, Benelli, Minghelli, Poggi, Noonan, Albini, Tosetti: "Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 9, pp. 710-22, (2014) (PubMed).

Sobrino-Plata, Carrasco-Gil, Abadía, Escobar, Álvarez-Fernández, Hernández: "The role of glutathione in mercury tolerance resembles its function under cadmium stress in Arabidopsis." in: Metallomics : integrated biometal science, Vol. 6, Issue 2, pp. 356-66, (2014) (PubMed).

Tomasi, Ryoo, Yang, Iglesias Ara, Ko, Lu: "Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice." in: Free radical biology & medicine, Vol. 68, pp. 148-58, (2014) (PubMed).

Aliases for GCLC 抗体

glutamate-cysteine ligase catalytic subunit (GCLC) 抗体
glutamate-cysteine ligase, catalytic subunit (gclc) 抗体
Glutamate-cysteine ligase catalytic subunit (Gclc) 抗体
gamma glutamylcysteine synthetase (LbGCS) 抗体
gamma glutamylcysteine synthetase (gcsA) 抗体
glutamate-cysteine ligase, catalytic subunit L homeolog (gclc.L) 抗体
glutamate-cysteine ligase, catalytic subunit S homeolog (gclc.S) 抗体
gamma-glutamylcysteine synthetase (GSH1) 抗体
glutamate-cysteine ligase, catalytic subunit (Gclc) 抗体
glutamate-cysteine ligase catalytic subunit (Gclc) 抗体
2259 抗体
cb1049 抗体
CG2259 抗体
D9Wsu168e 抗体
DDBDRAFT_0186120 抗体
DDBDRAFT_0231403 抗体
DDB_0186120 抗体
DDB_0231403 抗体
Dmel\\CG2259 抗体
DmGCLC 抗体
DmGCS 抗体
DmGCSh 抗体
fe36e11 抗体
GCL 抗体
GCLC 抗体
gclc 抗体
GCLc 抗体
Gcs 抗体
GCS 抗体
GCSh 抗体
Gcsh 抗体
Ggcs-hs 抗体
GLCL 抗体
GLCL-H 抗体
GLCLC 抗体
Glclc 抗体
MGC146287 抗体
wu:fe36e11 抗体
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