FMR1 抗体
(Fragile X Mental Retardation 1 (FMR1))
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010].
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Latest Publications for our FMR1 抗体
: "Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain." in: Molecular psychiatry, (2018) (PubMed).: "A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14." in: Neuroscience, Vol. 349, pp. 64-75, (2018) (PubMed).
: "RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC." in: PLoS genetics, Vol. 12, Issue 9, pp. e1006306, (2017) (PubMed).
: "Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP." in: eNeuro, Vol. 3, Issue 6, (2017) (PubMed).
: "Comparison of Equivalence between Two Commercially Available S499-Phosphorylated FMRP Antibodies in Mice." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143134, (2016) (PubMed).
: "Fragile X Mental Retardation Protein expression in the retina is regulated by light." in: Experimental eye research, Vol. 146, pp. 72-82, (2016) (PubMed).
: "FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity." in: PLoS ONE, Vol. 9, Issue 5, pp. e96956, (2015) (PubMed).
: "Profiling Chlamydomonas metabolism under dark, anoxic H2-producing conditions using a combined proteomic, transcriptomic, and metabolomic approach." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5431-51, (2014) (PubMed).
: "A quantitative homogeneous assay for fragile X mental retardation 1 protein." in: Journal of neurodevelopmental disorders, Vol. 5, Issue 1, pp. 8, (2013) (PubMed).
: "Fragile X Protein is required for inhibition of insulin signaling and regulates glial-dependent neuroblast reactivation in the developing brain." in: Brain research, Vol. 1462, pp. 151-61, (2012) (PubMed).
Aliases for FMR1 抗体
CG6203 gene product from transcript CG6203-RC (Fmr1) 抗体fragile X mental retardation 1 (FMR1) 抗体
fragile X mental retardation 1 (Fmr1) 抗体
fragile X mental retardation 1 (fmr1) 抗体
fragile X mental retardation syndrome 1 (Fmr1) 抗体
AT24755 抗体
BcDNA:GM08679 抗体
CG6203 抗体
cg6203 抗体
dFMR 抗体
dfmr 抗体
dFMR1 抗体
dFmr1 抗体
dfmr1 抗体
dFMRP 抗体
dFmrp 抗体
dFXR 抗体
dfxr 抗体
dFXR1 抗体
dfxr1 抗体
dFXRP 抗体
Dmel\\CG6203 抗体
dmfr1 抗体
EP(3)3517 抗体
FMR 抗体
fmr 抗体
Fmr-1 抗体
FMR1 抗体
fmr1 抗体
FMRP 抗体
FMRp 抗体
Fmrp 抗体
FRAXA 抗体
FXR 抗体
POF 抗体
POF1 抗体
zFMR1 抗体
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