FMR1 抗体 (C-Term)
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北京 101111
Quick Overview for FMR1 抗体 (C-Term) (ABIN2778786)
抗原
See all FMR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- FMR1 Antibody - C-terminal region
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序列
- GGGFKGNDDH SRTDNRPRNP REAKGRTTDG SLQNTSSEGS RLRTGKDRNQ
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against FMR1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human FMR1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40380-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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别名
- FMR1
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背景
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Background Information: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Gene Name: fragile X mental retardation 1
Alternative Symbols: POF, FMRP, POF1, FRAXA
Protein Name: fragile X mental retardation protein 1
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分子量
- 28kDa
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基因ID
- 2332
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NCBI登录号
- NP_001172004
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UniProt
- Q06787
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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