FMR1 抗体 (C-Term)
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- 抗原 See all FMR1 抗体
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FMR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QIGASSRPPP NRTDKEKGYV TDDGQGMGRG SRPYRNRGHG RRGPGYTSES
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Fmr1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Rat
- Top Product
- Discover our top product FMR1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 593 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
- 别名
- Fmr1 (FMR1 产品)
- 别名
- AT24755 antibody, BcDNA:GM08679 antibody, CG6203 antibody, Dmel\\CG6203 antibody, EP(3)3517 antibody, FMR antibody, FMR1 antibody, FMRP antibody, FMRp antibody, FXR antibody, Fmrp antibody, cg6203 antibody, dFMR antibody, dFMR1 antibody, dFMRP antibody, dFXR antibody, dFXR1 antibody, dFXRP antibody, dFmr1 antibody, dFmrp antibody, dfmr antibody, dfmr1 antibody, dfxr antibody, dfxr1 antibody, dmfr1 antibody, fmr antibody, fmr1 antibody, FRAXA antibody, POF antibody, POF1 antibody, zFMR1 antibody, Fmr-1 antibody, CG6203 gene product from transcript CG6203-RC antibody, fragile X mental retardation 1 antibody, fragile X mental retardation syndrome 1 antibody, Fmr1 antibody, FMR1 antibody, fmr1 antibody
- 背景
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Fmr1 is a translation repressor. Fmr1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression. RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.Fmr1 is associated with polysomes. Fmr1 is involved in the transport of mRNA from the nucleus to the cytoplasm. Fmr1 binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
Alias Symbols: FMRP, Fmr1
Protein Interaction Partner: Ubc,
Protein Size: 593 - 分子量
- 67 kDa
- 基因ID
- 24948
- NCBI登录号
- NM_052804, NP_434691
- UniProt
- Q80WE1
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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