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ERBB3 抗体

(Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
ERBB3 抗体  (AA 707-964) ERBB3 抗体  (AA 707-964) ERBB3 抗体 (AA 707-964) (ABIN7440773)

ERBB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

ERBB3 抗体  (N-Term) ERBB3 抗体  (N-Term) ERBB3 抗体 (N-Term) (ABIN391949)

ERBB3 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01467 unconjugated

ERBB3 抗体  (pTyr1289) ERBB3 抗体  (pTyr1289) ERBB3 抗体 (pTyr1289) (ABIN747113)

ERBB3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

ERBB3 抗体 by Grade

Find ERBB3 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ERBB3 抗体 by 适用

Find ERBB3 抗体 for a variety of species such as anti-Human ERBB3, anti-Rat ERBB3, anti-Mouse ERBB3. The species listed below are among those available. Click on a link to go to the corresponding products.

ERBB3 抗体 by 应用范围

Find ERBB3 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

ERBB3 抗体 by 抗体来源

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ERBB3 抗体 by 抗原表位

Find ERBB3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ERBB3 抗体 by 克隆形成能力

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ERBB3 抗体 by 克隆

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ERBB3 抗体 by 标记

Find ERBB3 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ERBB3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7440773
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (4)
  • (5)
Cat. No. ABIN391949
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
  • (4)
Cat. No. ABIN747113
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN560779
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6261585
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN3029524
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
  • (2)
  • (2)
Cat. No. ABIN686767
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
  • (3)
Cat. No. ABIN800628
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7008552
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7138931
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN515376
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF, FACS
Validations
  • (3)
Cat. No. ABIN185461
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN790478
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN790479
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (2)
Cat. No. ABIN969112
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our ERBB3 抗体

Memon, Gilliver, Borre, Sundquist, Sundquist, Nexo, Sorensen: "Soluble HER3 predicts survival in bladder cancer patients." in: Oncology letters, Vol. 15, Issue 2, pp. 1783-1788, (2018) (PubMed).

Cao, Chen, Chen, Xiong: "Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients." in: BMC cancer, Vol. 17, Issue 1, pp. 841, (2018) (PubMed).

Zomerman, Plasschaert, Diks, Lourens, Meeuwsen-de Boer, Hoving, den Dunnen, de Bont: "Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141381, (2015) (PubMed).

Liu, Leng, Gunasekaran, Pentony, Shen, Howard, Stoops, Manchulenko, Razinkov, Liu, Fanslow, Hu, Sun, Hasegawa, Clark, Foltz, Yan: "A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism." in: The Journal of biological chemistry, (2015) (PubMed).

Sie, den Dunnen, Lourens, Meeuwsen-de Boer, Scherpen, Zomerman, Kampen, Hoving, de Bont: "Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122555, (2015) (PubMed).

Cheng, Terai, Kageyama, Ozaki, McCue, Sato, Aplin: "Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma." in: Cancer research, Vol. 75, Issue 13, pp. 2737-48, (2015) (PubMed).

Davies, Holmes, Lomo, Steinkamp, Kang, Muller, Wilson: "High incidence of ErbB3, ErbB4, and MET expression in ovarian cancer." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 33, Issue 4, pp. 402-10, (2014) (PubMed).

Mimura, Shiraishi, Mueller, Izawa, Kua, So, Yong, Fujii, Seliger, Kiessling, Kono: "The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 12, pp. 6261-72, (2013) (PubMed).

Lee, Chin, Li: "Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking." in: The Journal of cell biology, Vol. 199, Issue 5, pp. 799-816, (2012) (PubMed).

MacLeod, Elgadi, Bossi, Sankar, Pisio, Agopsowicz, Sharon, Graham, Hitt: "HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice." in: Cancer gene therapy, Vol. 19, Issue 12, pp. 888-98, (2012) (PubMed).

Aliases for ERBB3 抗体

erb-b2 receptor tyrosine kinase 3 (ERBB3) 抗体
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) 抗体
erb-b2 receptor tyrosine kinase 3 (Erbb3) 抗体
c-erbB-3 抗体
c-erbB3 抗体
C76256 抗体
ErbB-3 抗体
Erbb-3 抗体
ERBB3 抗体
erbB3-S 抗体
Erbb3r 抗体
HER3 抗体
Her3 抗体
LCCS2 抗体
MDA-BF-1 抗体
nuc-ErbB3 抗体
p45-sErbB3 抗体
p85-sErbB3 抗体
p180-ErbB3 抗体
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