This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008].
Schoenmakers, Agostini, Mitchell, Schoenmakers, Papp, Rajanayagam, Padidela, Ceron-Gutierrez, Doffinger, Prevosto, Luan, Montano, Lu, Castanet, Clemons, Groeneveld, Castets, Karbaschi, Aitken, Dixon et al.: "Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. ..." in: The Journal of clinical investigation, Vol. 120, Issue 12, pp. 4220-35, (2010) (PubMed).
Aliases for EPT1 抗体
selenoprotein I (SELENOI) 抗体 selenoprotein I (Selenoi) 抗体 4933402G07Rik 抗体 AI448296 抗体 AI452230 抗体 C79563 抗体 D5Wsu178e 抗体 EPT1 抗体 hEPT1 抗体 mKIAA1724 抗体 RGD1560938 抗体 SELI 抗体 SEPI 抗体