ErbB2/Her2 抗体
(Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ErbB2/Her2 抗体 (AA 980-1230) | 人 | 兔 Polyclonal |
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| Rockland Original | ErbB2/Her2 抗体 (Extracellular Domain) | 人 | 兔 Monoclonal |
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| ErbB2/Her2 抗体 (pTyr1127) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pTyr1005) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (Center) | 人, 小鼠, 大鼠, 犬 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pTyr1248) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (AA 641-690) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pTyr1196) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pTyr1112) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pSer1151) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pThr1172) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pSer1107) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pTyr1139) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (pTyr1222) | 人 | 兔 Polyclonal |
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| ErbB2/Her2 抗体 (Cy5.5) | 人 | 小鼠 Monoclonal |
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| ErbB2/Her2 抗体 (AbBy Fluor® 750) | 人 | 小鼠 Monoclonal |
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| ErbB2/Her2 抗体 (AbBy Fluor® 594) | 人 | 小鼠 Monoclonal |
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| ErbB2/Her2 抗体 (AbBy Fluor® 680) | 人 | 小鼠 Monoclonal |
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| ErbB2/Her2 抗体 (Biotin) | 人 | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 980-1230
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- Supplier Product No.
- Rockland 900-c01-b37
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- SP3
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Extracellular Domain
Rockland Original
Primary Antibody
- WB (Western Blotting: 有验证图片)
- DB (Dot Blot: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr1127
Primary Antibody
- WB (Western Blotting: 有验证图片)
- DB (Dot Blot: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr1005
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 犬
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 有验证图片)
- DB (Dot Blot: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr1248
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 641-690
Primary Antibody
- WB (Western Blotting: 有验证图片)
- DB (Dot Blot: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr1196
Primary Antibody
- WB (Western Blotting: 有验证图片)
- DB (Dot Blot: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pTyr1112
Primary Antibody
- WB (Western Blotting: 有验证图片)
- DB (Dot Blot: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pSer1151
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- DB (Dot Blot: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pThr1172
Primary Antibody
- WB (Western Blotting: 有验证图片)
- DB (Dot Blot: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pSer1107
Primary Antibody
- WB (Western Blotting: 有验证图片)
- DB (Dot Blot: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pTyr1139
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pTyr1222
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5C9
- 标记
- Cy5.5
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5C9
- 标记
- AbBy Fluor® 750
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5C9
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5C9
- 标记
- AbBy Fluor® 680
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 13H9
- 标记
- Biotin
- 抗体亚型
- IgG
Latest Publications for our ErbB2/Her2 抗体
: "The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity." in: Nature communications, Vol. 9, Issue 1, pp. 3049, (2019) (PubMed).
: "Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma." in: Neuro-oncology, Vol. 20, Issue 4, pp. 506-518, (2019) (PubMed).
: "An Organoid-Based Preclinical Model of Human Gastric Cancer." in: Cellular and molecular gastroenterology and hepatology, Vol. 7, Issue 1, pp. 161-184, (2019) (PubMed).
: "Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer." in: Cancers, Vol. 11, Issue 12, (2019) (PubMed).
: "Single nucleotide variant profiles of viable single circulating tumour cells reveal CTC behaviours in breast cancer." in: Oncology reports, Vol. 39, Issue 5, pp. 2147-2159, (2018) (PubMed).
: "GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 80, (2018) (PubMed).
: "ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 15, pp. E3129-E3138, (2018) (PubMed).
: "Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients." in: Journal of Cancer, Vol. 8, Issue 2, pp. 227-239, (2017) (PubMed).
: "Development of a highly specific HER2 monoclonal antibody for immunohistochemistry using protein microarray chips." in: Biochemical and biophysical research communications, Vol. 484, Issue 2, pp. 248-254, (2017) (PubMed).
: "HER2/ERBB2 immunoreactivity in human retinoblastoma." in: Tumour biology, Vol. 37, Issue 5, pp. 6135-42, (2016) (PubMed).
: "Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma." in: Neuro-oncology, Vol. 20, Issue 4, pp. 506-518, (2019) (PubMed).
: "An Organoid-Based Preclinical Model of Human Gastric Cancer." in: Cellular and molecular gastroenterology and hepatology, Vol. 7, Issue 1, pp. 161-184, (2019) (PubMed).
: "Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer." in: Cancers, Vol. 11, Issue 12, (2019) (PubMed).
: "Single nucleotide variant profiles of viable single circulating tumour cells reveal CTC behaviours in breast cancer." in: Oncology reports, Vol. 39, Issue 5, pp. 2147-2159, (2018) (PubMed).
: "GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 80, (2018) (PubMed).
: "ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 15, pp. E3129-E3138, (2018) (PubMed).
: "Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients." in: Journal of Cancer, Vol. 8, Issue 2, pp. 227-239, (2017) (PubMed).
: "Development of a highly specific HER2 monoclonal antibody for immunohistochemistry using protein microarray chips." in: Biochemical and biophysical research communications, Vol. 484, Issue 2, pp. 248-254, (2017) (PubMed).
: "HER2/ERBB2 immunoreactivity in human retinoblastoma." in: Tumour biology, Vol. 37, Issue 5, pp. 6135-42, (2016) (PubMed).
Aliases for ErbB2/Her2 抗体
erb-b2 receptor tyrosine kinase 2 (ERBB2) 抗体erb-b2 receptor tyrosine kinase 2 (Erbb2) 抗体
erb-b2 receptor tyrosine kinase 2 (erbb2) 抗体
c-erbB2 抗体
c-neu 抗体
CD340 抗体
erb2 抗体
Erbb-2 抗体
HER-2 抗体
HER-2/neu 抗体
HER2 抗体
mKIAA3023 抗体
MLN 19 抗体
NEU 抗体
Neu 抗体
NGL 抗体
TKR1 抗体
wu:fv70f10 抗体
zgc:63601 抗体
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