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ErbB2/Her2 抗体

(Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].

489 results :

ErbB2/Her2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7444448
 
ErbB2/Her2 适用: 人, 小鼠, 大鼠, 犬, 猴, 马, Pig, 兔, Cow, Hamster, Avian, Cat, 小鸡, 驴, 山羊, 豚鼠, 绵羊 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN6254225
 
ErbB2/Her2 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 3B1 unconjugated
产品编号 ABIN515370
 
ErbB2/Her2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256630
 
ErbB2/Her2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6255774
 
ErbB2/Her2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256054
 
ErbB2/Her2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6140248
 
ErbB2/Her2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ERBB2-3078 unconjugated
产品编号 ABIN6939319
 
ErbB2/Her2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ERBB2-2452 unconjugated
产品编号 ABIN6939316
 
ErbB2/Her2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E1 unconjugated
产品编号 ABIN515369
 
ErbB2/Her2 适用: 人 ELISA, IF, FACS, Coat 宿主: 小鼠 Monoclonal HRB2-282 unconjugated
产品编号 ABIN6939327
 
ErbB2/Her2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6C2 unconjugated
Pubmed 1 reference
产品编号 ABIN969111
 
ErbB2/Her2 适用: 人 WB, ELISA, IF, DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029500
 
ErbB2/Her2 适用: 人, 小鼠 WB, ELISA, DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029502
 
ErbB2/Her2 适用: 人 WB, ELISA, IF, DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029498
 
ErbB2/Her2 适用: 人 WB, ELISA, IF, DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029493
 
ErbB2/Her2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029510
 
ErbB2/Her2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7434233
 
ErbB2/Her2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C16 unconjugated
产品编号 ABIN7426373
 
ErbB2/Her2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7139094
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Flow Cytometry (FACS)
    • Immunofluorescence (IF)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Dot Blot (DB)
    • Immunocytochemistry (ICC)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Immunochromatography (IC)
    • Coating (Coat)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • Immunoelectron Microscopy (IEM)
    • Staining Methods (StM)
    • Proximity Ligation Assay (PLA)
    • Cellular Assay (CA)
    • Heat-induced Epitope Retrieval (HIER)
    • Immunoassay (IA)
    • Immunostaining (ISt)
    • Luminex Assay (LMNX)
    • Test (T)
    • In Vivo Imaging (IVI)
    • Multiple Reaction Monitoring (MRM)
  • 适用
    • Human
    • Rat
    • Mouse
    • Dog
    • Monkey
    • Horse
    • Cow
    • Hamster
    • Pig
    • Rabbit
    • Avian
    • Cat
    • Chicken
    • Donkey
    • Gibbon
    • Goat
    • Gorilla
    • Guinea Pig
    • Sheep
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
    • Rat
    • Sheep
    • Chicken
    • Human
    • Humanized
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
    • Chimeric
  • 克隆
    • 13H9
    • 1A4
    • 5C9
    • HRB2-258
    • ERB2-776
    • HRB2-273
    • 24D2
    • 9G6
    • FWP51
    • 19G5
    • 3B5
    • ICR55
    • 11H9
    • 12K88
    • 19D2
    • 5F6
    • 9-00E-010
    • 9B9D8
    • C12
    • C15
    • C16
    • C19
    • C20
    • C3
    • ERBB2-2452
    • ERBB2-3078
    • HRB2-282
    • RB40075
    • RB50280
    • SPM172
    • 0-N-211
    • 10G9
    • 11A7
    • 11C99
    • 12B9
    • 1423CT594-76-52
    • 14C3
    • 1A064
    • 1D9
    • 24B5
    • 25E7
    • 27E43
    • 31E43
    • 3B1
    • 3C9
    • 3F11
    • 3F30
    • 3F38
    • 4D5V8
    • 4E1
    Please use search to find more...
  • 抗原表位
    • pTyr1221
    • pTyr1222
    • Extracellular Domain
    • pThr686
    • pTyr1248
    • C-Term
    • pTyr1112
    • pTyr877
    • AA 155-205
    • AA 1210-1255
    • N-Term
    • AA 23-372
    • AA 311-462
    • pTyr1139
    • AA 153-598
    • AA 676-1255
    • AA 23-652
    • AA 376-578
    • pTyr1196
    • AA 380-582
    • AA 531-559
    • Tyr1248
    • pSer1151
    • pThr1172
    • pTyr1005
    • pTyr1127
    • pTyr1140
    • AA 21-52
    • AA 22-121
    • AA 377-579
    • AA 750-987
    • Thr686
    • Tyr1221
    • Tyr877
    • pThr1166
    • pThr1168
    • AA 1100-1150
    • AA 1227-1255
    • AA 1236-1268
    • AA 1240-1260
    • AA 1242-1255
    • AA 1243-1255
    • AA 1246-1250
    • AA 23-419
    • AA 23-653
    • AA 29-64
    • AA 30-59
    • AA 875-879
    • Cytoplasmic Domain
    • Internal Region
    Please use search to find more...
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • HRP
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • CF®405S
    • CF®488A
    • CF®568
    • CF®594
    • CF®640R
    • CF®647
    • PE
    • APC
  • 抗体亚型
    • IgG
    • IgG1
    • Ig Fraction
    • IgG1 kappa
    • IgG2a kappa
    • IgG2b
    • IgG2b kappa
    • IgG2a
    • IgG kappa
    • kappa
    • IgG2
    • IgY
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Fragment
    • Fab fragment
    • Fc fragment
  • Grade
    • Verified
    • KD Validated
  • Supplier
    • antibodies-online
    • Signalway
    • USBio
    • Acris
    • Abcepta
    • Biotium
    • Abbexa
    • NSJ Bioreagents
    • Biomatik
    • OriGene
    • FabGennix
    • Assay Biotechnology Company, Inc.
    • Boster Bio
    • ProSci
    • RayBiotech
    • Cloud-Clone
    • Cohesion Biosciences
    • Abeomics
    • Angio-Proteomie
    • Rockland
    • CUSABIO
    • Covalab
    • RevMAb Biosciences

Latest Publications for our ErbB2/Her2 抗体

Helsen, Hammill, Lau, Mwawasi, Afsahi, Bezverbnaya, Newhook, Hayes, Aarts, Bojovic, Denisova, Kwiecien, Brain, Derocher, Milne, Nelson, Bramson: "The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity." in: Nature communications, Vol. 9, Issue 1, pp. 3049, (2019) (PubMed).

Bielamowicz, Fousek, Byrd, Samaha, Mukherjee, Aware, Wu, Orange, Sumazin, Man, Joseph, Hegde, Ahmed: "Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma." in: Neuro-oncology, Vol. 20, Issue 4, pp. 506-518, (2019) (PubMed).

Steele, Chakrabarti, Wang, Biesiada, Holokai, Chang, Nowacki, Hawkins, Mahe, Sundaram, Shroyer, Medvedovic, Helmrath, Ahmad, Zavros: "An Organoid-Based Preclinical Model of Human Gastric Cancer." in: Cellular and molecular gastroenterology and hepatology, Vol. 7, Issue 1, pp. 161-184, (2019) (PubMed).

Erlangga, Wolff, Poth, Peltzer, Nahnsen, Spielberg, Timrott, Woller, Kühnel, Manns, Saborowski, Vogel, Saborowski: "Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer." in: Cancers, Vol. 11, Issue 12, (2019) (PubMed).

Wang, Guo, Feng, Zhang, Xiao, Di, Chen, Zhang: "Single nucleotide variant profiles of viable single circulating tumour cells reveal CTC behaviours in breast cancer." in: Oncology reports, Vol. 39, Issue 5, pp. 2147-2159, (2018) (PubMed).

Li, Ma, Zheng, Zhang: "GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 80, (2018) (PubMed).

Wang, Her, Hu, Chen, Tung, Wu, Hsu, Lee, Jin, Hwang, Chen, Huang, Liao: "ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 15, pp. E3129-E3138, (2018) (PubMed).

Scrima, Zito Marino, Oliveira, Marinaro, La Mantia, Rocco, De Marco, Malanga, De Rosa, Rizzuto, Botti, Franco, Zoppoli, Viglietto: "Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients." in: Journal of Cancer, Vol. 8, Issue 2, pp. 227-239, (2017) (PubMed).

Qi, Zhou, Lu, Yuan, Li, Wu, Huang, Shen, Zhao, Fu, Chu, Wang, Ren, Ma, Chen: "Development of a highly specific HER2 monoclonal antibody for immunohistochemistry using protein microarray chips." in: Biochemical and biophysical research communications, Vol. 484, Issue 2, pp. 248-254, (2017) (PubMed).

Seigel, Sharma, Hackam, Shah: "HER2/ERBB2 immunoreactivity in human retinoblastoma." in: Tumour biology, Vol. 37, Issue 5, pp. 6135-42, (2016) (PubMed).

Aliases for ErbB2/Her2 抗体

erb-b2 receptor tyrosine kinase 2 (ERBB2) 抗体
erb-b2 receptor tyrosine kinase 2 (Erbb2) 抗体
erb-b2 receptor tyrosine kinase 2 (erbb2) 抗体
c-erbB2 抗体
c-neu 抗体
CD340 抗体
erb2 抗体
Erbb-2 抗体
HER-2 抗体
HER-2/neu 抗体
HER2 抗体
mKIAA3023 抗体
MLN 19 抗体
NEU 抗体
Neu 抗体
NGL 抗体
TKR1 抗体
wu:fv70f10 抗体
zgc:63601 抗体
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