31 Insulin Induced Gene 1 (INSIG1) 抗体 from 9 manufacturers are available on www.antibodies-online.cn.
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alternative names and synonyms associated with INSIG1
insulin induced gene 1 (INSIG1) 抗体
insulin induced gene 1 (insig1) 抗体
insulin induced gene 1 L homeolog (insig1.L) 抗体
insulin induced gene 1 (Insig1) 抗体
Protein level used designations for INSIG1
insulin induced gene 1
, insulin-induced gene 1 protein
, INSIG-1 membrane protein
, growth response protein (CL-6)
, immediate-early protein CL-6
, insulin-induced growth response protein CL-6