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Serum-expressed apolipoprotein B-100 (显示 APOB 蛋白) protein, C9 Complement, and gelsolin (显示 GSN 蛋白) can be used for differential diagnosis of Barrertts esophagus and adenocarcinoma of esophagus.
Patients with advanced atrophic AMD (显示 AMD1 蛋白) carried these rare variants more frequently than patients with neovascular AMD (显示 AMD1 蛋白) (11 of 93 [11.8%] vs 40 of 835 [4.8%]; P = .04).
Data indicate that complement C9 binds to the ATPase domain of mortalin (显示 HSPA9 蛋白).
Borrelial CspA binds the human terminal complement components C7 and C9 and blocks assembly and membrane insertion of the terminal complement complex (TCC (显示 SFXN1 蛋白)).
Caveolin-1 (显示 CAV1 蛋白) and dynamin-2 (显示 DNM2 蛋白) are essential for removal of the complement C5b-9 complex via endocytosis.
the haploinsufficiency of C9, a terminal complement complex component, engenders reduced intraocular secretion of VEGF (显示 VEGFA 蛋白) and decreased risk for CNV development.
It was concluded that variations in the complement component 9 gene are unlikely to influence clearance of chronic hepatitis B virus infection and hepatocellular carcinoma occurrence.
Mapping the intermedilysin-human CD59 (显示 CD59 蛋白) receptor interface reveals a deep correspondence with the binding site on CD59 (显示 CD59 蛋白) for complement binding proteins C8alpha and C9.
These results suggested that the lack of membrane attack complex because of an Arg95Stop mutation of the complement component 9 gene predisposed patients to pathognomonic glomerulonephritis.
Complement C5b-9 induce a JNK (显示 MAPK8 蛋白)/Bid (显示 BID 蛋白)-dependent and JNK (显示 MAPK8 蛋白)-independent necrotic cell death.
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.
complement component C9
, complement protein C9
, complement component 9 L homeolog