C5 蛋白
(Complement Component 5 (C5))
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| C5 Protein (AA 19-1676) (His tag) | 人 | HEK-293 Cells |
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| C5 Protein (AA 19-1676, full length) (His tag) | 人 | Mammalian Cells |
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| C5 Protein (AA 1550-1661) (GST tag) | 人 | 小麦胚 |
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| C5 Protein (AA 679-755) | 小鼠 | 大肠杆菌（E. Coli） |
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| C5 Protein (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| C5 Protein (His-SUMO Tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 679-755) | 小鼠 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 678-751) | 人 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 678-751) | 人 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 19-1676) (His tag) | 人 | HEK-293 Cells |
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| C5 Protein (AA 19-1676) (His tag) | 人 | HEK-293 Cells |
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| C5 Protein (AA 678-751) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 679-755) | 小鼠 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 679-755) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 1541-1688) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 19-350) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 1055-1513) | 人 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 1055-1513) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| C5 Protein (AA 19-1676) (His tag) | Cynomolgus | HEK-293 Cells |
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| C5 Protein (AA 19-1676) (His tag) | 人 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AcA (Activity Assay: 有验证图片)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- AcA (Activity Assay: 所列应用)
- CC (Cell Culture: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Latest Publications for our C5 蛋白
: "Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 8, pp. 4308-16, (2013) (PubMed).
Aliases for C5 蛋白
complement C5 (C5) 蛋白complement component 5 (c5) 蛋白
complement component 5 (C5) 蛋白
hemolytic complement (Hc) 蛋白
C5 蛋白
C5a 蛋白
C5b 蛋白
CPAMD4 蛋白
Hc 蛋白
He 蛋白
LOC565774 蛋白
RGD1561905 蛋白
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