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The complement C7 rs6876739 CC genotypes and mannan-binding lectin (MBL2 (显示 MBL2 蛋白)) gene polymorphisms of liver donors were significantly associated with bacterial infection in recipients.
Complement proteins C7 and CFH (显示 CFH 蛋白) control the stemness of liver cancer cells via LSF (显示 TFCP2 蛋白)-1 pathway.
Borrelial CspA binds the human terminal complement components C7 and C9 and blocks assembly and membrane insertion of the terminal complement complex (TCC (显示 SFXN1 蛋白)).
Complement C5b-9 induce a JNK (显示 MAPK8 蛋白)/Bid (显示 BID 蛋白)-dependent and JNK (显示 MAPK8 蛋白)-independent necrotic cell death.
To determine transcriptional regulation of the human complement component C7, a 1 kb promoter fragment was cloned and the transcription start site was determined. C7 is expressed by the hepatoma-derived cell line Hep-3B, but not by Hep-G2.
The interaction between the factor I domain of C7 and the C345C domain at the C terminus of the C5 alpha-chain (显示 FCGRT 蛋白) plays an essential role in complement membrane attack complex formation and complement lytic activity.
recurrence of fulminant meningococcal disease in a complement component C7-deficient patient
Cell cycle induction by C5b-9 in aortic endothelial cells is RGC-32 (显示 C13orf15 蛋白) dependent and this is in part through regulation of Akt (显示 AKT1 蛋白) and growth factor release.
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection.
complement component C7
, complement C7
, complement component 7
, complement component C7-like