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Clathrin-Ordered Protein 产品

(Clathrin-Ordered Protein (COP))

Categories

Caspase inhibitor. Acts as a regulator of procaspase- 1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro- inflammatory cytokine response. Also able to inhibit CASP1- mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

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Featured Clathrin-Ordered Protein Categories

Clathrin-Ordered Protein 抗体

High quality antibodies with extensive validation data.

Recommended Clathrin-Ordered Protein 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN2237945
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN2237957
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
Cat. No. ABIN2237943
Quantity 50 μg
Datasheet Datasheet

Recommended Clathrin-Ordered Protein 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Staphylococcus epidermidis
Source Yeast
Validations
Cat. No. ABIN1637512
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Clathrin-Ordered Protein Products

Druilhe, Srinivasula, Razmara, Ahmad, Alnemri: "Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins." in: Cell death and differentiation, Vol. 8, Issue 6, pp. 649-57, (2001) (PubMed).

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