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Claudin 18 产品

(Claudin 18 (CLDN18))
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010].

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Featured Claudin 18 Categories

Claudin 18 抗体

High quality antibodies with extensive validation data.

Claudin 18 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Claudin 18 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Claudin 18 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7147896
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7147892
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN214745
Quantity 50 μg
Datasheet Datasheet

Recommended Claudin 18 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954823
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954824
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN511594
Quantity 96 tests
Datasheet Datasheet

Recommended Claudin 18 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349600
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349601
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393226
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Claudin 18 Products

Lee, Hong, Jang: "N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression." in: The Korean journal of internal medicine, Vol. 35, Issue 5, pp. 1229-1237, (2020) (PubMed).

Kim, Kim, Rhee, Bae, Cho, Lee, Kang: "Gastric-type expression signature in serrated pathway-associated colorectal tumors." in: Human pathology, Vol. 46, Issue 5, pp. 643-56, (2015) (PubMed).

Jun, Kim, Jung, Choi, Chin: "Expression of claudin-7 and loss of claudin-18 correlate with poor prognosis in gastric cancer." in: International journal of surgery (London, England), Vol. 12, Issue 2, pp. 156-62, (2014) (PubMed).

Synonyms and alternative names related to Claudin 18

claudin 18 L homeolog (cldn18.L), claudin 18 (CLDN18), claudin 18 (Cldn18), claudin-18, CLDN18, SFTA5, SFTPJ

Protein level used designations for Claudin 18

  • claudin 18
  • claudin-18
  • surfactant associated 5
  • surfactant associated protein J
  • surfactant, pulmonary associated protein J
  • claudin 18-like
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