Claudin 18 产品
(Claudin 18 (CLDN18))
Categories
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010].
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Featured Claudin 18 Categories
Claudin 18 抗体
High quality antibodies with extensive validation data.
Claudin 18 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Claudin 18 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Claudin 18 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7147896
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7147892
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN214745
Quantity
50 μg
Datasheet
Datasheet
Recommended Claudin 18 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954823
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954824
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN511594
Quantity
96 tests
Datasheet
Datasheet
Recommended Claudin 18 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349601
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349600
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3098757
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Claudin 18 Products
: "N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression." in: The Korean journal of internal medicine, Vol. 35, Issue 5, pp. 1229-1237, (2020) (PubMed).: "Gastric-type expression signature in serrated pathway-associated colorectal tumors." in: Human pathology, Vol. 46, Issue 5, pp. 643-56, (2015) (PubMed).
: "Expression of claudin-7 and loss of claudin-18 correlate with poor prognosis in gastric cancer." in: International journal of surgery (London, England), Vol. 12, Issue 2, pp. 156-62, (2014) (PubMed).
Synonyms and alternative names related to Claudin 18
claudin 18 L homeolog (cldn18.L), claudin 18 (CLDN18), claudin 18 (Cldn18), claudin-18, CLDN18, SFTA5, SFTPJProtein level used designations for Claudin 18
- claudin 18
- claudin-18
- surfactant associated 5
- surfactant associated protein J
- surfactant, pulmonary associated protein J
- claudin 18-like
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