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Claudin 16 产品

(Claudin 16 (CLDN16))
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28. [provided by RefSeq, Jun 2010].

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Featured Claudin 16 Categories

Claudin 16 抗体

High quality antibodies with extensive validation data.

Claudin 16 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Claudin 16 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Claudin 16 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN524133
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN564659
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN654394
Quantity 400 μL
Datasheet Datasheet

Recommended Claudin 16 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965845
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954822
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1745303
Quantity 96 tests
Datasheet Datasheet

Recommended Claudin 16 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349597
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349596
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3119489
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Claudin 16 Products

Peng, Rao, Adelman, Rizzolo: "Claudin-19 and the barrier properties of the human retinal pigment epithelium." in: Investigative ophthalmology & visual science, Vol. 52, Issue 3, pp. 1392-403, (2011) (PubMed).

Wang, Zhang, Maminishkis, Dong, Zhi, Li, Zhao, Majerciak, Gaur, Chen, Miller: "MicroRNA-204/211 alters epithelial physiology." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 5, pp. 1552-71, (2010) (PubMed).

Synonyms and alternative names related to Claudin 16

claudin 16 (CLDN16), claudin 16 (Cldn16), claudin-16, CLDN16, HOMG3, PCLN1, Pcln1

Protein level used designations for Claudin 16

  • claudin 16
  • PCLN-1
  • claudin-16
  • hypomagnesemia 3, with hypercalciuria and nephrocalcinosis
  • paracellin-1
  • CL-16
  • H59D2a protein
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