Clathrin-Ordered Protein 抗体
(Clathrin-Ordered Protein (COP))
Caspase inhibitor. Acts as a regulator of procaspase- 1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro- inflammatory cytokine response. Also able to inhibit CASP1- mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Clathrin-Ordered Protein (COP) (AA 1-97) 抗体 | 人 | 小鼠 Polyclonal |
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| Clathrin-Ordered Protein (COP) (AA 1-97) 抗体 | 人 | 兔 Polyclonal |
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| Clathrin-Ordered Protein (COP) (AA 1-98) 抗体 | 人 | 小鼠 Monoclonal |
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| Clathrin-Ordered Protein (COP) (C-Term) 抗体 | 人 | 山羊 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-97
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-97
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3E10
- 标记
- unconjugated
- 抗体亚型
- IgG2b kappa
- 抗原表位
- AA 1-98
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- C-Term
Latest Publications for our Clathrin-Ordered Protein 抗体
: "Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins." in: Cell death and differentiation, Vol. 8, Issue 6, pp. 649-57, (2001) (PubMed).
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