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CD86 蛋白

(CD86)
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
CD86 Protein (CD86) (AA 26-247) (Fc Tag) CD86 Protein (CD86) (AA 26-247) (Fc Tag) CD86 Protein (CD86) (AA 26-247) (Fc Tag) (ABIN7273897)

CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

CD86 Protein (CD86) (His-Avi Tag) CD86 Protein (CD86) (His-Avi Tag) CD86 Protein (CD86) (His-Avi Tag) (ABIN7273898)

CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

CD86 Protein (CD86) (AA 26-240) (His tag) CD86 Protein (CD86) (AA 26-240) (His tag) CD86 Protein (CD86) (AA 26-240) (His tag) (ABIN7273896)

CD86 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

CD86 蛋白 by Grade

Find CD86 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CD86 蛋白 by Origin

Find CD86 蛋白 for a variety of species such as anti-Human CD86, anti-Mouse CD86, anti-Cynomolgus CD86. The species listed below are among those available. Click on a link to go to the corresponding products.

CD86 蛋白 by Source

Here you will find CD86 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CD86 蛋白 by 蛋白类型

Here you can find CD86 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CD86 蛋白 by 应用范围

Find CD86 蛋白 validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CD86 蛋白 by 生物活性

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Popular CD86 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273897
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273898
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273896
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus, Rhesus Monkey
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN2180853
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (3)
Cat. No. ABIN2180621
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7273899
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN1348720
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN2870717
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN2180618
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN3137664
Quantity 200 μg
Datasheet Datasheet
Reactivity Rhesus Monkey
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320996
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320769
Quantity 50 μg
Datasheet Datasheet
Reactivity Rabbit
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320993
Quantity 50 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320949
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122216
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CD86 蛋白

Li, Li, Chu, Wang: "A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope." in: mAbs, Vol. 12, Issue 1, pp. 1725365, (2020) (PubMed).

Zhao, Lee, Lin, Gassen, Xu, Huang, Xiao, Bonorino, Lu, Bui, Hui: "PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways." in: Immunity, Vol. 51, Issue 6, pp. 1059-1073.e9, (2019) (PubMed).

Gmyrek, Pingel, Choi, Green: "Functional analysis of acquired CD28 mutations identified in cutaneous T cell lymphoma." in: Cellular immunology, Vol. 319, pp. 28-34, (2017) (PubMed).

Aliases for CD86 蛋白

CD86 molecule (CD86) 蛋白
CD86 antigen (Cd86) 蛋白
CD86 molecule (Cd86) 蛋白
integrin subunit alpha 2b (Itga2b) 蛋白
B7 蛋白
B7-2 蛋白
B7.2 蛋白
B70 蛋白
Cd28l2 蛋白
CD28LG2 蛋白
CLS1 蛋白
ETC-1 蛋白
LAB72 蛋白
Ly-58 蛋白
Ly58 蛋白
MB7 蛋白
MB7-2 蛋白
TS/A-2 蛋白
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