CDKN3 抗体
(Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
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Latest Publications for our CDKN3 抗体
: "High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 5, pp. 1263-74, (2010) (PubMed).: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).
: "KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction." in: Biochemical and biophysical research communications, Vol. 351, Issue 1, pp. 216-22, (2006) (PubMed).
: "Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1." in: Biochemical and biophysical research communications, Vol. 349, Issue 2, pp. 573-81, (2006) (PubMed).
: "Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP..." in: The Journal of biological chemistry, Vol. 280, Issue 17, pp. 17235-42, (2005) (PubMed).
: "Abolishment of the interaction between cyclin-dependent kinase 2 and Cdk-associated protein phosphatase by a truncated KAP mutant." in: Biochemical and biophysical research communications, Vol. 305, Issue 2, pp. 311-4, (2003) (PubMed).
: "Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression." in: Molecular and cellular biology, Vol. 20, Issue 5, pp. 1723-32, (2000) (PubMed).
: "Aberrant transcripts of the cyclin-dependent kinase-associated protein phosphatase in hepatocellular carcinoma." in: Cancer research, Vol. 60, Issue 17, pp. 4697-700, (2000) (PubMed).
Aliases for CDKN3 抗体
cyclin dependent kinase inhibitor 3 (CDKN3) 抗体cyclin-dependent kinase inhibitor 3 (CDKN3) 抗体
cyclin-dependent kinase inhibitor 3 (cdkn3) 抗体
cyclin-dependent kinase inhibitor 3 (Cdkn3) 抗体
cyclin dependent kinase inhibitor 3 (Cdkn3) 抗体
inhibitor/interactor with cyclin-dependent kinase (ICK6) 抗体
2410006H10Rik 抗体
CDI1 抗体
CDKN3 抗体
CIP2 抗体
inhibitor/interactor with cyclin-dependent kinase 抗体
K24G6.15 抗体
K24G6_15 抗体
KAP 抗体
KAP1 抗体
KIP-RELATED PROTEIN 3 抗体
KRP3 抗体
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