CDKN3 产品
(Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))
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The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
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Featured CDKN3 Categories
CDKN3 抗体
High quality antibodies with extensive validation data.
CDKN3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CDKN3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDKN3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6260728
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN3022822
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7148919
Quantity
100 μg
Datasheet
Datasheet
Recommended CDKN3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966182
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955168
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648167
Quantity
96 tests
Datasheet
Datasheet
Recommended CDKN3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122543
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349027
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349026
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our CDKN3 Products
: "High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 5, pp. 1263-74, (2010) (PubMed).: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).
: "KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction." in: Biochemical and biophysical research communications, Vol. 351, Issue 1, pp. 216-22, (2006) (PubMed).
: "Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1." in: Biochemical and biophysical research communications, Vol. 349, Issue 2, pp. 573-81, (2006) (PubMed).
: "Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP..." in: The Journal of biological chemistry, Vol. 280, Issue 17, pp. 17235-42, (2005) (PubMed).
: "Abolishment of the interaction between cyclin-dependent kinase 2 and Cdk-associated protein phosphatase by a truncated KAP mutant." in: Biochemical and biophysical research communications, Vol. 305, Issue 2, pp. 311-4, (2003) (PubMed).
: "Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression." in: Molecular and cellular biology, Vol. 20, Issue 5, pp. 1723-32, (2000) (PubMed).
: "Aberrant transcripts of the cyclin-dependent kinase-associated protein phosphatase in hepatocellular carcinoma." in: Cancer research, Vol. 60, Issue 17, pp. 4697-700, (2000) (PubMed).
Synonyms and alternative names related to CDKN3
cyclin dependent kinase inhibitor 3 (CDKN3), cyclin-dependent kinase inhibitor 3 (CDKN3), cyclin-dependent kinase inhibitor 3 (cdkn3), cyclin-dependent kinase inhibitor 3 (Cdkn3), cyclin dependent kinase inhibitor 3 (Cdkn3), inhibitor/interactor with cyclin-dependent kinase (ICK6), 2410006H10Rik, CDI1, CDKN3, CIP2, inhibitor/interactor with cyclin-dependent kinase, K24G6.15, K24G6_15, KAP, KAP1, KIP-RELATED PROTEIN 3, KRP3Protein level used designations for CDKN3
- CDK2-associated dual specificity phosphatase
- CDK2-associated dual-specificity phosphatase
- Cdk-associated protein phosphatase
- cyclin-dependent kinase interacting protein 2
- cyclin-dependent kinase interactor 1
- cyclin-dependent kinase-interacting protein 2
- kinase associated phosphatase
- kinase-associated phosphatase
- cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)
- cyclin-dependent kinase inhibitor 3
- Kinase-associated phosphatase
- Inhibitor/interactor of CDK protein 6
- KIP-related protein 3
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