CDK2 蛋白
(Cyclin-Dependent Kinase 2 (CDK2))
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
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30 results :
custom-made
CDK2
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
CDK2
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CDK2
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AA, AP
1 image
2 references
CDK2
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
CDK2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 % as determined by reducing SDS-PAGE.
CDK2
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 85 % as determined by reducing SDS-PAGE.
CDK2
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
CDK2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 97 %
SDS, WB, Imm, PC
custom-made
CDK2
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
CDK2
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Latest Publications for our CDK2 蛋白
: "TarIKGC: A Target Identification Tool Using Semantics-Enhanced Knowledge Graph Completion with Application to CDK2 Inhibitor Discovery." in: Journal of medicinal chemistry, Vol. 68, Issue 2, pp. 1793-1809, (2025) (PubMed).: "A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization." in: Human mutation, Vol. 31, Issue 11, pp. E1825-35, (2010) (PubMed).
: "Peptide aptamers in label-free protein detection: 2. Chemical optimization and detection of distinct protein isoforms." in: Analytical chemistry, Vol. 81, Issue 9, pp. 3314-20, (2009) (PubMed).
: "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 5070-85, (2006) (PubMed).
Aliases for CDK2 蛋白
cyclin dependent kinase 2 (CDK2) 蛋白cyclin-dependent kinase 2 (Cdk2) 蛋白
cyclin dependent kinase 2 (Cdk2) 蛋白
cyclin-dependent kinase 2 (cdk2) 蛋白
cyclin-dependent kinase 2 S homeolog (cdk2.S) 蛋白
cyclin-dependent kinase 2 (CDK2) 蛋白
A630093N05Rik 蛋白
cdk2L 蛋白
CDKN2 蛋白
eg1 蛋白
p33(CDK2) 蛋白
wu:fa10c02 蛋白
zgc:56598 蛋白
zgc:77684 蛋白
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