CD45RB 抗体
(CD45RB)
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CD45RB 抗体 | 人 | 小鼠 Monoclonal |
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| Recombinant CD45RB 抗体 | 人 | 兔 Monoclonal |
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| CD45RB 抗体 | 人 | 小鼠 Monoclonal |
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Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- CDLA45RB-2R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
Latest Publications for our CD45RB 抗体
: "Pivotal advance: CD45RB glycosylation is specifically regulated during human peripheral B cell differentiation." in: Journal of leukocyte biology, Vol. 90, Issue 1, pp. 5-19, (2011) (PubMed).
: "Involvement of CD45 in DNA fragmentation in apoptosis induced by mitochondrial perturbing agents." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 2, pp. 197-212, (2008) (PubMed).
: "Collagen-mediated survival signaling is modulated by CD45 in Jurkat T cells." in: Molecular immunology, Vol. 44, Issue 15, pp. 3682-90, (2007) (PubMed).
: "Use of flow cytometry to identify monoclonal antibodies that recognize conserved epitopes on orthologous leukocyte differentiation antigens in goats, llamas, and rabbits." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 123-30, (2007) (PubMed).
: "Screening of anti-human leukocyte monoclonal antibodies for reactivity with equine leukocytes." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 63-80, (2007) (PubMed).
: "Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells." in: Clinical and experimental immunology, Vol. 150, Issue 3, pp. 509-17, (2007) (PubMed).
: "CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis." in: Brain pathology (Zurich, Switzerland), Vol. 16, Issue 4, pp. 256-65, (2006) (PubMed).
: "Involvement of CD45 in DNA fragmentation in apoptosis induced by mitochondrial perturbing agents." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 2, pp. 197-212, (2008) (PubMed).
: "Collagen-mediated survival signaling is modulated by CD45 in Jurkat T cells." in: Molecular immunology, Vol. 44, Issue 15, pp. 3682-90, (2007) (PubMed).
: "Use of flow cytometry to identify monoclonal antibodies that recognize conserved epitopes on orthologous leukocyte differentiation antigens in goats, llamas, and rabbits." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 123-30, (2007) (PubMed).
: "Screening of anti-human leukocyte monoclonal antibodies for reactivity with equine leukocytes." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 63-80, (2007) (PubMed).
: "Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells." in: Clinical and experimental immunology, Vol. 150, Issue 3, pp. 509-17, (2007) (PubMed).
: "CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis." in: Brain pathology (Zurich, Switzerland), Vol. 16, Issue 4, pp. 256-65, (2006) (PubMed).
Aliases for CD45RB 抗体
protein tyrosine phosphatase, receptor type C (PTPRC) 抗体protein tyrosine phosphatase, receptor type, C (Ptprc) 抗体
B220 抗体
CD45 抗体
Cd45 抗体
CD45R 抗体
GP180 抗体
L-CA 抗体
LCA 抗体
loc 抗体
Ly-5 抗体
LY5 抗体
Lyt-4 抗体
T200 抗体
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