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CCM2 蛋白

(Cerebral Cavernous Malformation 2 (CCM2))
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009].

9 results

custom-made CCM2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7559524
 
custom-made CCM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7552982
 
CCM2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
产品编号 ABIN7122246
 
CCM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
产品编号 ABIN1348424
 
CCM2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE
产品编号 ABIN1589765
 
CCM2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % pure SDS
产品编号 ABIN2128400
 
custom-made CCM2 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3126365
 
custom-made CCM2 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3090690
 
CCM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2725248
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • 抗原表位
    • AA 1-444
    • AA 1-453
    • AA 66-353
    • Transcript Variant 2
  • 标记
    • His tag
    • Strep Tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene

Aliases for CCM2 蛋白

CCM2 scaffolding protein (CCM2) 蛋白
CCM2 scaffolding protein (Ccm2) 蛋白
cerebral cavernous malformation 2 (Ccm2) 蛋白
malcavernin (LOC100304744) 蛋白
cerebral cavernous malformation 2 (ccm2) 蛋白
BC029157 蛋白
C7orf22 蛋白
CCM2 蛋白
malcavernin 蛋白
OSM 蛋白
TUF2 蛋白
vtn 蛋白
zgc:110233 蛋白
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