Caspase 4 抗体
(Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Caspase 4 抗体 (Alexa Fluor 594) | 人 | 兔 Polyclonal |
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| Caspase 4 抗体 (Alexa Fluor 488) | 人 | 兔 Polyclonal |
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| Caspase 4 抗体 (Center) | 人 | 兔 Polyclonal |
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| Caspase 4 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| Caspase 4 抗体 (AA 91-105) | 人 | 兔 Polyclonal |
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| Caspase 4 抗体 | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Caspase 4 抗体 | 人 | 兔 Polyclonal |
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| Caspase 4 抗体 | 人 | 小鼠 Monoclonal |
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| Caspase 4 抗体 (AA 75-124) | 人 | 兔 Polyclonal |
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| Caspase 4 抗体 (Cleaved-Ala290) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 91-105
Primary Antibody
- WB (Western Blotting: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 75-124
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Cleaved-Ala290
Latest Publications for our Caspase 4 抗体
: "Entamoeba histolytica-induced IL-1β secretion is dependent on caspase-4 and gasdermin D." in: Mucosal immunology, Vol. 12, Issue 2, pp. 323-339, (2019) (PubMed).
: "Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis." in: Cell reports, Vol. 26, Issue 6, pp. 1614-1626.e5, (2019) (PubMed).
: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).
: "E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation." in: Cell death and differentiation, (2019) (PubMed).
: "IRF2 transcriptionally induces GSDMD expression for pyroptosis." in: Science signaling, Vol. 12, Issue 582, (2019) (PubMed).
: "Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis." in: The Journal of experimental medicine, Vol. 216, Issue 11, pp. 2562-2581, (2019) (PubMed).
: "Trimetazidine Attenuates Cardiac Dysfunction in Endotoxemia and Sepsis by Promoting Neutrophil Migration." in: Frontiers in immunology, Vol. 9, pp. 2015, (2019) (PubMed).
: "Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-κB, MAPK and NLRP3 inflammasome signaling pathways." in: The Journal of nutritional biochemistry, Vol. 74, pp. 108229, (2019) (PubMed).
: "Obesity-associated NLRC4 inflammasome activation drives breast cancer progression." in: Nature communications, Vol. 7, pp. 13007, (2018) (PubMed).
: "Copper Regulates the Canonical NLRP3 Inflammasome." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 5, pp. 1607-1617, (2018) (PubMed).
: "Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis." in: Cell reports, Vol. 26, Issue 6, pp. 1614-1626.e5, (2019) (PubMed).
: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).
: "E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation." in: Cell death and differentiation, (2019) (PubMed).
: "IRF2 transcriptionally induces GSDMD expression for pyroptosis." in: Science signaling, Vol. 12, Issue 582, (2019) (PubMed).
: "Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis." in: The Journal of experimental medicine, Vol. 216, Issue 11, pp. 2562-2581, (2019) (PubMed).
: "Trimetazidine Attenuates Cardiac Dysfunction in Endotoxemia and Sepsis by Promoting Neutrophil Migration." in: Frontiers in immunology, Vol. 9, pp. 2015, (2019) (PubMed).
: "Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-κB, MAPK and NLRP3 inflammasome signaling pathways." in: The Journal of nutritional biochemistry, Vol. 74, pp. 108229, (2019) (PubMed).
: "Obesity-associated NLRC4 inflammasome activation drives breast cancer progression." in: Nature communications, Vol. 7, pp. 13007, (2018) (PubMed).
: "Copper Regulates the Canonical NLRP3 Inflammasome." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 5, pp. 1607-1617, (2018) (PubMed).
Aliases for Caspase 4 抗体
caspase 4 (CASP4) 抗体caspase 4 (Casp4) 抗体
caspase 4, apoptosis-related cysteine peptidase (CASP4) 抗体
caspase 4, apoptosis-related cysteine peptidase (Casp4) 抗体
caspase-4 (LOC100731032) 抗体
CASP1 抗体
CASP4 抗体
Casp4 抗体
Casp11 抗体
CASP13 抗体
Caspl 抗体
ICE(rel)II 抗体
ICEREL-II 抗体
ICH-2 抗体
ich-3 抗体
Mih1/TX 抗体
TX 抗体
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