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Caspase 4 抗体 (AA 75-124)

The 兔 多克隆 anti-Caspase 4 antibody (ABIN1453020) specifically detects Caspase 4 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN1453020
发货至: 中国
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Quick Overview for Caspase 4 抗体 (AA 75-124) (ABIN1453020)

抗原

See all Caspase 4 (CASP4) 抗体
Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

适用

  • 95
  • 45
  • 29
  • 15
  • 1
人

宿主

  • 116
  • 9
  • 2
  • 1
  • 1
兔

克隆类型

  • 105
  • 23
多克隆

标记

  • 59
  • 18
  • 13
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This Caspase 4 antibody is un-conjugated

应用范围

  • 117
  • 54
  • 49
  • 31
  • 30
  • 15
  • 11
  • 8
  • 5
  • 3
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 13
    • 12
    • 12
    • 9
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-124

    原理

    Caspase-4 Antibody

    特异性

    Caspase-4 Polyclonal Antibody detects endogenous levels of Caspase-4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human Caspase-4. AA range:75-124

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

    别名

    Caspase-4

    背景

    Synonyms: CASP4, ICH2, Caspase-4, CASP-4, ICE(rel)-II, Protease ICH-2, Protease TX

    Background: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

    Gene Name: CASP4

    Protein Name: Caspase4

    分子量

    43 kDa

    基因ID

    837

    OMIM

    602664

    UniProt

    P49662

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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