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Caspase 4 抗体

(Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
Caspase 4 抗体  (AA 290-377) Caspase 4 抗体  (AA 290-377) Caspase 4 抗体 (AA 290-377) (ABIN7438061)

CASP4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

Caspase 4 抗体  (AA 82-226) Caspase 4 抗体  (AA 82-226) Caspase 4 抗体 (AA 82-226) (ABIN7146946)

CASP4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

Caspase 4 抗体  (AA 81-266) Caspase 4 抗体  (AA 81-266) Caspase 4 抗体 (AA 81-266) (ABIN6137966)

CASP4 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

Caspase 4 抗体 by Grade

Find Caspase 4 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Caspase 4 抗体 by 适用

Find Caspase 4 抗体 for a variety of species such as anti-Human Caspase 4, anti-Mouse Caspase 4, anti-Cow Caspase 4. The species listed below are among those available. Click on a link to go to the corresponding products.

Caspase 4 抗体 by 应用范围

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Caspase 4 抗体 by 抗原表位

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Caspase 4 抗体 by 克隆形成能力

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Caspase 4 抗体 by 克隆

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Caspase 4 抗体 by 标记

Find Caspase 4 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Caspase 4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (3)
Cat. No. ABIN7438061
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7146946
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN6137966
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IP, FACS
Validations
  • (3)
Cat. No. ABIN2745522
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7186100
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN7434005
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7436840
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN185284
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN1326998
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN5693193
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7426751
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243615
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243616
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6745371
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), IF, EIA
Validations
  • (3)
Cat. No. ABIN499561
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our Caspase 4 抗体

Quach, Moreau, Sandall, Chadee: "Entamoeba histolytica-induced IL-1β secretion is dependent on caspase-4 and gasdermin D." in: Mucosal immunology, Vol. 12, Issue 2, pp. 323-339, (2019) (PubMed).

Wang, Lim, Kajikawa, Li, Vallance, Moutsopoulos, Chavakis, Hajishengallis: "Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis." in: Cell reports, Vol. 26, Issue 6, pp. 1614-1626.e5, (2019) (PubMed).

Pronin, Pham, An, Dvoriantchikova, Reshetnikova, Qiao, Kozhekbaeva, Reiser, Slepak, Shestopalov: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).

Liu, Zhang, Sun, Guo, Zhou: "E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation." in: Cell death and differentiation, (2019) (PubMed).

Kayagaki, Lee, Stowe, Kornfeld, ORourke, Mirrashidi, Haley, Watanabe, Roose-Girma, Modrusan, Kummerfeld, Reja, Zhang, Cho, Andrews, Morris, Goodnow, Bertram, Dixit: "IRF2 transcriptionally induces GSDMD expression for pyroptosis." in: Science signaling, Vol. 12, Issue 582, (2019) (PubMed).

Li, Wu, Yang, Wu, Ma, Liu, Moynagh, Wang, Hu, Yang: "Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis." in: The Journal of experimental medicine, Vol. 216, Issue 11, pp. 2562-2581, (2019) (PubMed).

Chen, Wang, Lai, Braunstein, He, Ruan, Yin, Wang, Cianflone, Ning, Chen, Wang: "Trimetazidine Attenuates Cardiac Dysfunction in Endotoxemia and Sepsis by Promoting Neutrophil Migration." in: Frontiers in immunology, Vol. 9, pp. 2015, (2019) (PubMed).

Castejon, Sánchez-Hidalgo, Aparicio-Soto, Montoya, Martín-LaCave, Fernández-Bolaños, Alarcón-de-la-Lastra: "Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-κB, MAPK and NLRP3 inflammasome signaling pathways." in: The Journal of nutritional biochemistry, Vol. 74, pp. 108229, (2019) (PubMed).

Kolb, Phan, Borcherding, Liu, Yuan, Janowski, Xie, Markan, Li, Potthoff, Fuentes-Mattei, Ellies, Knudson, Lee, Yeung, Cassel, Sutterwala, Zhang: "Obesity-associated NLRC4 inflammasome activation drives breast cancer progression." in: Nature communications, Vol. 7, pp. 13007, (2018) (PubMed).

Deigendesch, Zychlinsky, Meissner: "Copper Regulates the Canonical NLRP3 Inflammasome." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 5, pp. 1607-1617, (2018) (PubMed).

Aliases for Caspase 4 抗体

caspase 4 (CASP4) 抗体
caspase 4 (Casp4) 抗体
caspase 4, apoptosis-related cysteine peptidase (CASP4) 抗体
caspase 4, apoptosis-related cysteine peptidase (Casp4) 抗体
caspase-4 (LOC100731032) 抗体
CASP1 抗体
CASP4 抗体
Casp4 抗体
Casp11 抗体
CASP13 抗体
Caspl 抗体
ICE(rel)II 抗体
ICEREL-II 抗体
ICH-2 抗体
ich-3 抗体
Mih1/TX 抗体
TX 抗体
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