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CASC5 抗体

(Cancer Susceptibility Candidate 5 (CASC5))
The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11\;15)(q23\;q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jan 2013].
CASC5 抗体 CASC5 抗体 CASC5 抗体 (ABIN7256628)

CASC5 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

CASC5 抗体  (AA 1-300) CASC5 抗体  (AA 1-300) CASC5 抗体 (AA 1-300) (ABIN6137952)

CASC5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

CASC5 抗体  (AA 2251-2342) CASC5 抗体  (AA 2251-2342) CASC5 抗体 (AA 2251-2342) (ABIN760391)

CASC5 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

CASC5 抗体 by 适用

Find CASC5 抗体 for a variety of species such as anti-Mouse CASC5, anti-Human CASC5, anti-Rat CASC5. The species listed below are among those available. Click on a link to go to the corresponding products.

CASC5 抗体 by 应用范围

Find CASC5 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

CASC5 抗体 by 抗体来源

Find CASC5 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

CASC5 抗体 by 抗原表位

Find CASC5 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CASC5 抗体 by 克隆形成能力

Find available monoclonal or polyclonal CASC5 抗体. Click on a link to go to the corresponding products.

CASC5 抗体 by 克隆

Find CASC5 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

CASC5 抗体 by 标记

Find CASC5 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CASC5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7256628
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN6137952
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN760391
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN760393
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN886564
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN886561
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN886560
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2811117
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN886562
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN4999060
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN4999061
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN760394
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN760395
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN760396
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN760398
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CASC5 抗体

Itoh, Ikeda, Iemura, Amin, Kuriyama, Tanaka, Mizuno, Osakada, Haraguchi, Tanaka: "Lateral attachment of kinetochores to microtubules is enriched in prometaphase rosette and facilitates chromosome alignment and bi-orientation establishment." in: Scientific reports, Vol. 8, Issue 1, pp. 3888, (2019) (PubMed).

Milev, Hasaj, Saint-Dic, Snounou, Zhao, Sacher: "TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment." in: The Journal of cell biology, Vol. 209, Issue 2, pp. 221-34, (2015) (PubMed).

Zhang, Zhang, Gao, Wang, Jin, Wei, Saiyin, Wang, Peng, Ma, Tang, Wumaier, Yu, Dong, Huang, Yu, Wang: "ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments." in: Oncotarget, Vol. 6, Issue 39, pp. 41550-65, (2015) (PubMed).

Aliases for CASC5 抗体

kinetochore scaffold 1 (KNL1) 抗体
kinetochore scaffold 1 (Knl1) 抗体
Kinetochore null protein 1 (knl-1) 抗体
2310043D08Rik 抗体
5730505K17Rik 抗体
AF15Q14 抗体
CT29 抗体
D40 抗体
hKNL-1 抗体
hSpc105 抗体
KNL1 抗体
PPP1R55 抗体
Rad51 抗体
Spc7 抗体
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