Caspase 3 抗体
(Caspase 3 (CASP3))
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008].
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279 results :
CASP3
适用: 人, 小鼠, 大鼠
WB, IHC
宿主: 小鼠
Monoclonal
5E1
unconjugated
1 reference
1 validation
Independently Validated
CASP3
适用: 人
WB, IF, PLA
宿主: 兔
Polyclonal
unconjugated
1 reference
Latest Publications for our Caspase 3 抗体
: "Alpha-1-Antitrypsin Protects Vascular Grafts of Brain-Dead Rats Against Ischemia/Reperfusion Injury." in: The Journal of surgical research, Vol. 283, pp. 953-964, (2023) (PubMed).: "Baicalin Rescues Cognitive Dysfunction, Mitigates Neurodegeneration, and Exerts Anti-Epileptic Effects Through Activating TLR4/MYD88/Caspase-3 Pathway in Rats." in: Drug design, development and therapy, Vol. 15, pp. 3163-3180, (2022) (PubMed).
: "Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats." in: Stem cells international, Vol. 2022, pp. 7019088, (2022) (PubMed).
: "GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling." in: JCI insight, Vol. 5, Issue 3, (2021) (PubMed).
: "EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation." in: Cancer cell international, Vol. 21, Issue 1, pp. 531, (2021) (PubMed).
: "BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes." in: Cancer cell international, Vol. 21, Issue 1, pp. 230, (2021) (PubMed).
: "Distinct Expression Patterns of Apoptosis and Autophagy-Associated Proteins and Genes during Postnatal Development of Spiral Ganglion Neurons in Rat." in: Neural plasticity, Vol. 2020, pp. 9387560, (2021) (PubMed).
: "Investigating the Pharmacological Mechanisms of SheXiang XinTongNing Against Coronary Heart Disease Based on Network Pharmacology and Experimental Evaluation." in: Frontiers in pharmacology, Vol. 12, pp. 698981, (2021) (PubMed).
: "Protective effects of safranal on hypoxia/reoxygenation-induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway." in: Experimental and therapeutic medicine, Vol. 22, Issue 6, pp. 1400, (2021) (PubMed).
: "Modulation of COX-2 and NADPH oxidase-4 by alpha-lipoic acid ameliorates busulfan-induced pulmonary injury in rats." in: Heliyon, Vol. 7, Issue 10, pp. e08171, (2021) (PubMed).
Aliases for Caspase 3 抗体
caspase 3 (CASP3) 抗体caspase 3 (Casp3) 抗体
caspase 3 S homeolog (casp3.S) 抗体
caspase 3, apoptosis-related cysteine peptidase a (casp3a) 抗体
caspase 3, apoptosis-related cysteine peptidase (Casp3) 抗体
A830040C14Rik 抗体
AC-3 抗体
Apopain 抗体
CASP-3 抗体
casp3 抗体
Caspase-3 抗体
caspase-3 抗体
CC3 抗体
CPP32 抗体
CPP32B 抗体
Lice 抗体
mldy 抗体
SCA-1 抗体
xcpp32 抗体
Yama 抗体
zgc:100890 抗体
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