CARD8 抗体
(Caspase Recruitment Domain Family, Member 8 (CARD8))
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CARD8 抗体 (AA 221-320) (Biotin) | 人 | 兔 Polyclonal |
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| CARD8 抗体 (AA 221-320) (Cy5.5) | 人 | 兔 Polyclonal |
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| CARD8 抗体 (AA 20-69) | 人 | 兔 Polyclonal |
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| CARD8 抗体 (AA 1-392) | 人 | 小鼠 Polyclonal |
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| CARD8 抗体 (AA 1-392) | 人 | 兔 Polyclonal |
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| CARD8 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CARD8 抗体 | 人 | 小鼠 Monoclonal |
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| CARD8 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| CARD8 抗体 | 人 | 兔 Polyclonal |
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| CARD8 抗体 | 人 | 兔 Polyclonal |
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| CARD8 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| CARD8 抗体 | 人 | 小鼠 Monoclonal |
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| CARD8 抗体 (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CARD8 抗体 (Alexa Fluor 555) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CARD8 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CARD8 抗体 (Biotin) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CARD8 抗体 (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CARD8 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CARD8 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CARD8 抗体 | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 221-320
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5.5
- 抗体亚型
- IgG
- 抗原表位
- AA 221-320
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 20-69
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-392
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-392
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- DB (Dot Blot: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2108C2a
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Latest Publications for our CARD8 抗体
: "Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease." in: The Journal of clinical investigation, Vol. 128, Issue 5, pp. 1793-1806, (2018) (PubMed).
: "CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13952-8, (2002) (PubMed).
: "TUCAN/CARDINAL and DRAL participate in a common pathway for modulation of NF-kappaB activation." in: FEBS letters, Vol. 521, Issue 1-3, pp. 165-9, (2002) (PubMed).
: "TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer." in: The Journal of biological chemistry, Vol. 276, Issue 34, pp. 32220-9, (2001) (PubMed).
: "DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis." in: The Journal of cell biology, Vol. 151, Issue 3, pp. 495-506, (2000) (PubMed).
: "CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13952-8, (2002) (PubMed).
: "TUCAN/CARDINAL and DRAL participate in a common pathway for modulation of NF-kappaB activation." in: FEBS letters, Vol. 521, Issue 1-3, pp. 165-9, (2002) (PubMed).
: "TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer." in: The Journal of biological chemistry, Vol. 276, Issue 34, pp. 32220-9, (2001) (PubMed).
: "DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis." in: The Journal of cell biology, Vol. 151, Issue 3, pp. 495-506, (2000) (PubMed).
Aliases for CARD8 抗体
caspase recruitment domain family, member 8 (CARD8) 抗体caspase recruitment domain-containing protein 8 (LOC718594) 抗体
caspase recruitment domain family member 8 (CARD8) 抗体
CARD8 抗体
CARDINAL 抗体
DACAR 抗体
DAKAR 抗体
NDPP 抗体
NDPP1 抗体
TUCAN 抗体
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