CARD8 抗体 (N-Term)
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北京 101111
Quick Overview for CARD8 抗体 (N-Term) (ABIN2786065)
抗原
See all CARD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- CARD8 Antibody - N-terminal region
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序列
- LGGTFPGDIC SEENQIVSSY ASKVCFEIEE DYKNRQFLGP EGNVDVELID
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against CARD8. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CARD8
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anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibody
CARD8 适用: 人 WB, ICC, IP, FACS, DB 宿主: 小鼠 Monoclonal 2108C2a unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (Internal Region) antibodyCARD8 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (C-Term) antibodyCARD8 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibodyCARD8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibodyCARD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55119-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
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别名
- CARD8
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背景
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Background Information: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Gene Name: caspase recruitment domain family, member 8
Alternative Symbols: NDPP, DACAR, DAKAR, NDPP1, TUCAN, CARDINAL
Protein Name: Caspase recruitment domain-containing protein 8
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分子量
- 31kDa
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基因ID
- 22900
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UniProt
- Q9Y2G2
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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