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- 抗原 See all CARD8 抗体
- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LGGTFPGDIC SEENQIVSSY ASKVCFEIEE DYKNRQFLGP EGNVDVELID
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CARD8. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CARD8
- Top Product
- Discover our top product CARD8 Primary Antibody
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anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibody
CARD8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibodyCARD8 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (C-Term) antibodyCARD8 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibodyCARD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibodyCARD8 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
- 别名
- CARD8 (CARD8 产品)
- 别名
- CARD8 antibody, CARDINAL antibody, DACAR antibody, DAKAR antibody, NDPP antibody, NDPP1 antibody, TUCAN antibody, caspase recruitment domain family, member 8 antibody, caspase recruitment domain-containing protein 8 antibody, caspase recruitment domain family member 8 antibody, CARD8 antibody, LOC718594 antibody
- 背景
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The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Protein Interaction Partner: ELAVL1, CARD16, CARD8, CARD18, NLRP2, NLRP3, FHL2, CASP9, IKBKG, CASP1, CARD6,
Protein Size: 286 - 分子量
- 31 kDa
- 基因ID
- 22900
- 途径
- Positive Regulation of Endopeptidase Activity
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