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- 抗原 See all CARD8 抗体
- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- CARD8 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARD8.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Human CARD8 / Cardinal / TUCAN Peptide
- 亚型
- IgG
- Top Product
- Discover our top product CARD8 Primary Antibody
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anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibody
CARD8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibodyCARD8 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (C-Term) antibodyCARD8 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibodyCARD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Immunocytochemistry. Western Blot: CARD8 antibody can be used for detection of CARD8 at 2 μg/mL. K562 cell lysate can be used as Positive Control and a band at approximately 45 kDa canbe detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
- 别名
- CARD8 / NDPP1 (CARD8 产品)
- 别名
- CARD8 antibody, CARDINAL antibody, DACAR antibody, DAKAR antibody, NDPP antibody, NDPP1 antibody, TUCAN antibody, caspase recruitment domain family, member 8 antibody, caspase recruitment domain-containing protein 8 antibody, caspase recruitment domain family member 8 antibody, CARD8 antibody, LOC718594 antibody
- 背景
- Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD8. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis (1,2), and caspase-1 and its related proteins ICEBERG and pesudo-ICE (3). Although there are conflicting reports on whether CARD8 acts a pro- or anti-apoptotic protein (2,4), it has been suggested that it functions as an adaptor molecule regulating caspase-1 and NF-kappaB activation.Synonyms: Apoptotic protein NDPP-1, CARD-inhibitor of NF-kappa-B-activating ligand, CARDINAL, Caspase recruitment domain-containing protein 8, DACAR, KIAA0955, TUCAN, Tumor up-regulated CARD-containing antagonist of CASP9
- 基因ID
- 22900
- UniProt
- Q9Y2G2
- 途径
- Positive Regulation of Endopeptidase Activity
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