BRISC and BRCA1 A Complex Member 1 产品
(BRISC and BRCA1 A Complex Member 1 (BABAM1))
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Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36. component (By similarity).
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Featured BRISC and BRCA1 A Complex Member 1 Categories
BRISC and BRCA1 A Complex Member 1 抗体
High quality antibodies with extensive validation data.
BRISC and BRCA1 A Complex Member 1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
BRISC and BRCA1 A Complex Member 1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BRISC and BRCA1 A Complex Member 1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Dog, Guinea Pig, Horse, Human, Monkey, Mouse
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN6749759
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN949228
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN652514
Quantity
400 μL
Datasheet
Datasheet
Recommended BRISC and BRCA1 A Complex Member 1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1124171
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1124172
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1124173
Quantity
96 tests
Datasheet
Datasheet
Recommended BRISC and BRCA1 A Complex Member 1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7552631
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7563723
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122038
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our BRISC and BRCA1 A Complex Member 1 Products
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).Synonyms and alternative names related to BRISC and BRCA1 A Complex Member 1
BRISC and BRCA1 A complex member 1 (babam1), BRISC and BRCA1 A complex member 1 (BABAM1), BRISC and BRCA1 A complex member 1 L homeolog (babam1.L), BRISC and BRCA1 A complex member 1 (Babam1), 5430437P03Rik, C7H19orf62, c19orf62, C19orf62, merit40, MERIT40, Merit40, nba1, NBA1, zgc:100909Protein level used designations for BRISC and BRCA1 A Complex Member 1
- BRCA1-A complex subunit MERIT40
- BRISC and BRCA1-A complex member 1
- mediator of RAP80 interactions and targeting subunit of 40 kDa
- new component of the BRCA1-A complex
- mediator of Rap80 interactions and targeting 40 kDa
- new component of the BRCA1 A complex
- new component of the BRCAA1 A complex
- Uncharacterized protein C19orf62 homolog
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