(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008].
TNFRSF17
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
custom-made
TNFRSF17
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TNFRSF17
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
TNFRSF17
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
Huard, Tran, Benkhoucha, Manzin-Lorenzi, Santiago-Raber: "Selective APRIL blockade delays systemic lupus erythematosus in mouse." in: PLoS ONE, Vol. 7, Issue 2, pp. e31837, (2012) (PubMed).
Huard, Arlettaz, Ambrose, Kindler, Mauri, Roosnek, Tschopp, Schneider, French: "BAFF production by antigen-presenting cells provides T cell co-stimulation." in: International immunology, Vol. 16, Issue 3, pp. 467-75, (2004) (PubMed).
Huard, Schneider, Mauri, Tschopp, French: "T cell costimulation by the TNF ligand BAFF." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 11, pp. 6225-31, (2001) (PubMed).
Rennert, Schneider, Cachero, Thompson, Trabach, Hertig, Holler, Qian, Mullen, Strauch, Browning, Ambrose, Tschopp: "A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth." in: The Journal of experimental medicine, Vol. 192, Issue 11, pp. 1677-84, (2000) (PubMed).