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BCMA Protein (AA 1-53) (hFc Tag)

This Recombinant BCMA protein is expressed in HEK-293 Cells.
产品编号 ABIN7273936
发货至: 中国
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Quick Overview for BCMA Protein (AA 1-53) (hFc Tag) (ABIN7273936)

抗原

See all BCMA (TNFRSF17) 蛋白
BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

蛋白类型

Recombinant

生物活性

Active

宿主

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Cynomolgus, 猕猴

资源

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HEK-293 Cells

纯度

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 1-53

    标记

    This BCMA protein is labelled with hFc Tag.

    原理

    Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein

    序列

    Met1-Ala53

    产品特性

    Recombinant Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein is expressed from HEK293 with hFc (IgG1) at the C-Terminus.It contains Met1-Ala53.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Cynomolgus APRIL (Trimer) , His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque BCMA, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA (QC Test).,Immobilized Cynomolgus/Rhesus macaque BCMA, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-BCMA Antibody, hFc Tag with the EC50 of 9.1ng/ml determined by ELISA.,Cynomolgus/Rhesus macaque BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,Loaded Cynomolgus APRIL (Trimer), His-Avi Tag on Anti-His-Biosensor can bind Cynomolgus BCMA, hFc Tag with an affinity constant of 1.59 nM as determined in BLI assay (Gator® Prime).,The purity of Cynomolgus/Rhesus macaque BCMA is greater than 95% as determined by SEC-HPLC.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

    别名

    BCMA

    背景

    B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).

    分子量

    31.5 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.

    UniProt

    A0A2K5UD97
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