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BCMA Protein (AA 1-54) (Fc Tag)

TNFRSF17 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN2180644
发货至: 中国
  • 抗原 See all BCMA (TNFRSF17) 蛋白
    BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 1-54
    宿主
    • 42
    • 13
    • 6
    • 6
    • 2
    • 1
    • 1
    资源
    • 42
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This BCMA protein is labelled with Fc Tag.
    序列
    AA 1-54
    产品特性
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32 kDa. As a result of glycosylation, the protein migrates as 35-40 kDa under reducing (R) condition, and 66 kDa under non-reducing (NR) condition (SDS-PAGE).
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 0.1 EU per μg by the LAL method.
    Top Product
    Discover our top product TNFRSF17 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Berahovich, Liu, Zhou, Tsadik, Xu, Golubovskaya, Wu: "Hypoxia Selectively Impairs CAR-T Cells In Vitro." in: Cancers, Vol. 11, Issue 5, (2019) (PubMed).

    Berahovich, Zhou, Xu, Wei, Guan, Guan, Harto, Fu, Yang, Zhu, Li, Wu, Golubovskaya: "CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth." in: Cancers, Vol. 10, Issue 9, (2018) (PubMed).

  • 抗原
    BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
    别名
    BCMA (TNFRSF17 产品)
    别名
    TNFRSF17 Protein, BCM Protein, BCMA Protein, CD269 Protein, TNFRSF13A Protein, Tnfrsf13 Protein, Tnfrsf13a Protein, TNF receptor superfamily member 17 Protein, tumor necrosis factor receptor superfamily, member 17 Protein, Tnfrsf17 Protein, TNFRSF17 Protein
    背景
    Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
    分子量
    32.0 kDa
    NCBI登录号
    NP_001183
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