BCR 蛋白
(Breakpoint Cluster Region (BCR))
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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11 results
custom-made
BCR
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
BCR
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
BCR
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
custom-made
BCR
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Rockland Original
Aliases for BCR 蛋白
breakpoint cluster region (bcr) 蛋白BCR, RhoGEF and GTPase activating protein (BCR) 蛋白
BCR, RhoGEF and GTPase activating protein (bcr) 蛋白
breakpoint cluster region (Bcr) 蛋白
BCR, RhoGEF and GTPase activating protein (Bcr) 蛋白
5133400C09Rik 蛋白
AI561783 蛋白
AI853148 蛋白
ALL 蛋白
BCR 蛋白
BCR1 蛋白
CML 蛋白
D22S11 蛋白
D22S662 蛋白
mKIAA3017 蛋白
PHL 蛋白
si:dkey-83d9.7 蛋白
zK83D9.7 蛋白
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