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BCMA 产品

(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008].

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Featured BCMA Categories

BCMA 抗体

High quality antibodies with extensive validation data.

BCMA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

BCMA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BCMA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS, IP, IF
Validations
  • (5)
Cat. No. ABIN6961043
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN7172255
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7076067
Quantity 100 μL
Datasheet Datasheet

Recommended BCMA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960291
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970980
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975649
Quantity 96 tests
Datasheet Datasheet

Recommended BCMA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273940
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus, Rhesus Monkey
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273936
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273941
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BCMA Products

Berahovich, Liu, Zhou, Tsadik, Xu, Golubovskaya, Wu: "Hypoxia Selectively Impairs CAR-T Cells In Vitro." in: Cancers, Vol. 11, Issue 5, (2019) (PubMed).

Chapellier, Peña-Martínez, Ramakrishnan, Eriksson, Safaee-Talkhoncheh, Orsmark-Pietras, Lilljebjörn, Högberg, Hagström-Andersson, Fioretos, Larsson, Järås: "Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells." in: Haematologica, (2019) (PubMed).

Garfall, Stadtmauer, Hwang, Lacey, Melenhorst, Krevvata, Carroll, Matsui, Wang, Dhodapkar, Dhodapkar, Das, Vogl, Weiss, Cohen, Mangan, Ayers, Nunez-Cruz, Kulikovskaya, Davis, Lamontagne, Dengel, Kerr et al.: "Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma. ..." in: JCI insight, Vol. 3, Issue 8, (2018) (PubMed).

Bu, Singh, Choi, Ruella, Nunez-Cruz, Mansfield, Bennett, Barton, Wu, Zhang, Wang, Wei, Cogan, Ezell, Joshi, Latimer, Granda, Tschantz, Young, Huet, Richardson, Milone: "Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma." in: Oncotarget, Vol. 9, Issue 40, pp. 25764-25780, (2018) (PubMed).

Berahovich, Zhou, Xu, Wei, Guan, Guan, Harto, Fu, Yang, Zhu, Li, Wu, Golubovskaya: "CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth." in: Cancers, Vol. 10, Issue 9, (2018) (PubMed).

de la Varga Martínez, Rodríguez-Bayona, Añez, Medina Varo, Pérez Venegas, Brieva, Rodríguez: "Clinical relevance of circulating anti-ENA and anti-dsDNA secreting cells from SLE patients and their dependence on STAT-3 activation." in: European journal of immunology, Vol. 47, Issue 7, pp. 1211-1219, (2017) (PubMed).

Saulep-Easton, Vincent, Quah, Wei, Ting, Croce, Tam, Mackay: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." in: Leukemia, Vol. 30, Issue 1, pp. 163-72, (2016) (PubMed).

Laurent, Hoffmann, Kuhn, Cheng, Chu, Schmidt-Supprian, Hauck, Schuh, Krumbholz, Rübsamen, Wanngren, Khademi, Olsson, Alexander, Hiepe, Pfister, Weber, Jenne, Wekerle, Hohlfeld, Lichtenthaler, Meinl: "γ-Secretase directly sheds the survival receptor BCMA from plasma cells." in: Nature communications, Vol. 6, pp. 7333, (2015) (PubMed).

Hoffmann, Kuhn, Laurent, Hauck, Berer, Wendlinger, Krumbholz, Khademi, Olsson, Dreyling, Pfister, Alexander, Hiepe, Kümpfel, Crawford, Wekerle, Hohlfeld, Lichtenthaler, Meinl: "The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 2, pp. 542-52, (2015) (PubMed).

Khan, Hams, Floudas, Sparwasser, Weaver, Fallon: "PD-L1hi B cells are critical regulators of humoral immunity." in: Nature communications, Vol. 6, pp. 5997, (2015) (PubMed).

Synonyms and alternative names related to BCMA

TNF receptor superfamily member 17 (Tnfrsf17), TNF receptor superfamily member 17 (TNFRSF17), tumor necrosis factor receptor superfamily, member 17 (Tnfrsf17), BCM, BCMA, CD269, Tnfrsf13, TNFRSF13A, Tnfrsf13a, TNFRSF17

Protein level used designations for BCMA

  • tumor necrosis factor receptor superfamily member 17
  • tumor necrosis factor receptor superfamily, member 17
  • B cell maturation antigen
  • B-cell maturation factor
  • B-cell maturation protein
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