Aurora Kinase A 产品
(Aurora Kinase A (AURKA))
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The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Aurora Kinase A Categories
Aurora Kinase A 抗体
High quality antibodies with extensive validation data.
Aurora Kinase A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Aurora Kinase A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Aurora Kinase A 抗体
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Reactivity
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Cat. No.
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Datasheet
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Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (2)
- (5)
Cat. No.
ABIN563053
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (7)
Cat. No.
ABIN2855868
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, FACS, ICC
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Cat. No.
ABIN5611121
Quantity
0.1 mg
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Recommended Aurora Kinase A ELISA试剂盒
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Analytical Method
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Human
Analytical Method
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- (1)
Cat. No.
ABIN6965093
Quantity
96 tests
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Recommended Aurora Kinase A 蛋白
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Wheat germ
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Cat. No.
ABIN1346206
Quantity
25 μg
Datasheet
Datasheet
Reactivity
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Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570517
Quantity
5 μg
Datasheet
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Reactivity
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Source
Insect cells (Sf9)
Validations
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Cat. No.
ABIN5570516
Quantity
100 μg
Datasheet
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Latest Publications for our Aurora Kinase A Products
: "A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes." in: Science (New York, N.Y.), Vol. 364, Issue 6447, (2019) (PubMed).: "Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes." in: Current biology : CB, Vol. 28, Issue 1, pp. 130-139.e3, (2018) (PubMed).
: "Chromosome Segregation Is Biased by Kinetochore Size." in: Current biology : CB, Vol. 28, Issue 9, pp. 1344-1356.e5, (2018) (PubMed).
: "Aurora kinase A is essential for correct chromosome segregation in mouse zygote." in: Zygote (Cambridge, England), Vol. 24, Issue 3, pp. 326-37, (2016) (PubMed).
: "Loss of PKCδ Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/β-Catenin Pathway and Mcl-1 Accumulation." in: Molecular cancer therapeutics, Vol. 15, Issue 7, pp. 1713-25, (2016) (PubMed).
: "Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer." in: Oncotarget, (2016) (PubMed).
: "Aurora kinase A gene copy number is associated with the malignant transformation of colorectal adenomas but not with the serrated neoplasia progression." in: Human pathology, Vol. 46, Issue 3, pp. 411-8, (2015) (PubMed).
: "TACC3 Is Important for Correct Progression of Meiosis in Bovine Oocytes." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132591, (2015) (PubMed).
: "Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant ..." in: Cancer biology & therapy, Vol. 16, Issue 2, pp. 233-43, (2015) (PubMed).
: "TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma." in: Journal of gastroenterology, Vol. 49, Issue 8, pp. 1231-40, (2014) (PubMed).
Synonyms and alternative names related to Aurora Kinase A
aurora kinase A (AURKA), aurora kinase A (Aurka), aurora A (aurA), aurora kinase A L homeolog (aurka.L), aurora kinase A (aurka), hypothetical protein (Aurora-A), aurora kinase A S homeolog (aurka.S), 87A7-9/2, AIK, aik, AIRK1, ARK-1, ARK1, Ark1, ark1, AU019385, Aur-A, aur-A, aur-a, AURA, AurA, aurA, aura, AURKA, aurka, aurka-a, Aurora-A, AURORA2, aurora2, AW539821, Ayk1, BTAK, btak, CG3068, ck10, ck[10], Dmel\\CG3068, Eg2, IAK, IAK1, l(3)87Ac, l(3)ck10, pEg2, PPP1R47, STK6, Stk6, stk6, STK7, stk7, STK15, stk15, wu:fb37c10, wu:fc02c02, zgc:100912Protein level used designations for Aurora Kinase A
- ARK-1
- Aurora-A kinase
- IPL1-related kinase
- aurora 2
- aurora-related kinase 1
- aurora/IPL1-like kinase
- aurora/IPL1-related kinase 1
- breast tumor-amplified kinase
- breast-tumor-amplified kinase
- hARK1
- protein phosphatase 1, regulatory subunit 47
- serine/threonine kinase 6
- serine/threonine protein kinase 15
- serine/threonine-protein kinase 15
- serine/threonine-protein kinase 6
- serine/threonine-protein kinase aurora-A
- aurora A
- aurora family kinase 1
- ipl1- and aurora-related kinase 1
- serine/threonine-protein kinase Ayk1
- A-type aurora kinase
- AuroraA
- CG3068-PA
- aur-PA
- aurora A kinase
- aurora kinase
- aurora-A
- early-A
- fruhe2
- ratAurA
- serine/threonine protein kinase 6
- Aurora A
- aurora kinase A-A
- p46Eg265
- pEg2
- serine/threonine-protein kinase 6-A
- serine/threonine-protein kinase Eg2
- serine/threonine-protein kinase Eg2-A
- Aurora-A
- Serine/threonine-protein kinase 6
- hypothetical protein
- aurora kinase A
- fb37c10
- fc02c02
- aurora A kinase protein
- serine/threonine-protein kinase 6-like
- aurora kinase A-B
- serine/threonine-protein kinase 6-B
- serine/threonine-protein kinase Eg2-B
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