PPM1A 抗体 (AA 202-382)
(2 references)-
- 抗原 See all PPM1A 抗体
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
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抗原表位
- AA 202-382
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适用
- 人, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PPM1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human PPM1A (AA: 202-382) expressed in E. coli. ,
- 克隆位点
- 7F12
- 亚型
- IgG1
- Top Product
- Discover our top product PPM1A Primary Antibody
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anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) antibody
PPM1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal p6c7 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) antibodyPPM1A 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) antibodyPPM1A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-383) antibodyPPM1A 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) antibodyPPM1A 适用: 人, 小鼠 WB, ELISA, IP 宿主: 小鼠 Monoclonal p6c7 unconjugated
anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 107-156) antibodyPPM1A 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 小鸡, Pig, Bat, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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: "Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants." in: Biological psychiatry, Vol. 69, Issue 4, pp. 360-5, (2011) (PubMed).
: "PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation." in: Cellular signalling, Vol. 21, Issue 1, pp. 95-102, (2008) (PubMed).
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: "Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants." in: Biological psychiatry, Vol. 69, Issue 4, pp. 360-5, (2011) (PubMed).
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- 抗原
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
- 别名
- PPM1A (PPM1A 产品)
- 别名
- PP2C-ALPHA antibody, PP2CA antibody, PP2Calpha antibody, pp2ca1 antibody, ppp1r13b antibody, si:ch211-253p18.1 antibody, wu:fd42g12 antibody, zgc:153820 antibody, 2310003C21Rik antibody, 2900017D14Rik antibody, AI427932 antibody, AU017636 antibody, MMPa-2 antibody, MPPa-1 antibody, Pp2c1 antibody, pp2c-alpha antibody, pp2ca antibody, pp2calpha antibody, pp2ca2 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1A antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Ab antibody, protein phosphatase 1A, magnesium dependent, alpha isoform antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1A antibody, protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Aa antibody, PPM1A antibody, ppm1ab antibody, Ppm1a antibody, ppm1a.L antibody, ppm1aa antibody
- 背景
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Description: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Aliases: PP2CA, PP2Calpha, PP2C-ALPHA
- 分子量
- 42.4 kDa
- 基因ID
- 5494
- HGNC
- 5494
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