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SNCG (Breast Cancer-Specific Protein 1) 抗体

适用: 人 IHC, ELISA, WB 宿主: 小鼠 Monoclonal 1H10D2 unconjugated
产品编号 ABIN969490
发货至: 中国
  • 抗原
    SNCG (Breast Cancer-Specific Protein 1)
    适用
    宿主
    小鼠
    克隆类型
    • 1
    单克隆
    标记
    • 1
    非结合性
    应用范围
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of SNCG expressed in E. coli.
    克隆位点
    1H10D2
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Surgucheva, McMahon, Surguchov: "gamma-synuclein has a dynamic intracellular localization." in: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).

    Brown, Lasek: "Polylysine cross-links axoplasmic neurofilaments into tight bundles." in: Cell motility and the cytoskeleton, Vol. 31, Issue 1, pp. 9-21, (1995) (PubMed).

  • 抗原
    SNCG (Breast Cancer-Specific Protein 1)
    背景

    Description: SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

    Aliases: SR, BCSG1

    基因ID
    6623
    HGNC
    6623
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