SNCG (Breast Cancer-Specific Protein 1) 抗体
适用: 人
IHC, ELISA, WB
Monoclonal
unconjugated
(1 reference)-
- 抗原
- SNCG (Breast Cancer-Specific Protein 1)
- 适用
- 人
- 宿主
- 请咨询
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克隆类型
- 单克隆
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标记
- 非结合性
- 应用范围
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
- 特异性
- Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3)
- 纯化方法
- Antibodies are purified by protein A affinity chromatography
- 亚型
- IgG1
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anti-SNCG (Breast Cancer-Specific Protein 1) antibody
适用: 人 IHC, ELISA, WB 宿主: 小鼠 Monoclonal 1H10D2 unconjugated
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- 应用备注
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 储存条件
- -20 °C
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: "gamma-synuclein has a dynamic intracellular localization." in: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).
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: "gamma-synuclein has a dynamic intracellular localization." in: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).
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- 抗原
- SNCG (Breast Cancer-Specific Protein 1)
- 背景
- SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein. Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
- 基因ID
- 6623
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