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STAT6 抗体

STAT6 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7D3 unconjugated
产品编号 ABIN969423
发货至: 中国
  • 抗原 See all STAT6 抗体
    STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
    适用
    • 130
    • 70
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    人, 小鼠, 大鼠, 猴
    宿主
    • 112
    • 17
    • 4
    • 1
    小鼠
    克隆类型
    • 101
    • 32
    单克隆
    标记
    • 75
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    This STAT6 antibody is un-conjugated
    应用范围
    • 68
    • 43
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    • 27
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    • 19
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    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human STAT6 expressed in E. coli.
    克隆位点
    7D3
    亚型
    IgG1
    Top Product
    Discover our top product STAT6 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Ikeuchi, Kobayashi, Arakawa, Suzuki, Tamra, Morikawa: "Polymorphisms in interleukin-4-related genes in patients with minimal change nephrotic syndrome." in: Pediatric nephrology (Berlin, Germany), Vol. 24, Issue 3, pp. 489-95, (2009) (PubMed).

    Inomata, Into, Nakashima, Noguchi, Matsushita: "IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6- and SOCS-1-dependent mechanisms." in: Molecular immunology, Vol. 46, Issue 10, pp. 2080-9, (2009) (PubMed).

    Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

  • 抗原
    STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
    别名
    STAT6 (STAT6 产品)
    别名
    D12S1644 antibody, IL-4-STAT antibody, STAT6B antibody, STAT6C antibody, signal transducer and activator of transcription 6 antibody, signal transducer and activator of transcription 6-like antibody, STAT6 antibody, Stat6 antibody, LOC100859543 antibody
    背景

    Description: STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.

    Aliases: STAT6B, STAT6C, D12S1644, IL-4-STAT, STAT6

    分子量
    94 kDa
    基因ID
    6778
    HGNC
    6778
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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