IKK alpha 抗体 (AA 500-590)
Quick Overview for IKK alpha 抗体 (AA 500-590) (ABIN969054)
抗原
See all IKK alpha (CHUK) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 500-590
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原理
 - CHUK Antibody
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纯化方法
 - Ascitic fluid
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免疫原
 - Purified recombinant fragment of CHUK (aa500-590) expressed in E. Coli.
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亚型
 - IgG1
 
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应用备注
 - ELISA: 1/10000
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - Ascitic fluid containing 0.03 % sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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                                            : "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity."    in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, (2004)         (PubMed).        
 
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                                            : "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity."    in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, (2004)         (PubMed).        
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- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
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别名
 - CHUK
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背景
 - CHUK: conserved helix-loop-helix ubiquitous kinase. This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
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基因ID
 - 1147
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UniProt
 - O15111
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途径
 - PI3K-Akt Signaling, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
 
抗原
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