IKK alpha 抗体 (AA 411-745)
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- 抗原 See all IKK alpha (CHUK) 抗体
- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
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抗原表位
- AA 411-745
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IKK alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Human partial recombinant protein (AA 411-745) was used as the immunogen for this IKK alpha antibody.
- 亚型
- IgG
- Top Product
- Discover our top product CHUK Primary Antibody
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anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (C-Term) antibody
CHUK 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pSer176), (pSer177) antibodyCHUK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibodyCHUK 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibodyCHUK 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4B8 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibodyCHUK 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibodyCHUK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibodyCHUK 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3G12H9 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibodyCHUK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibodyCHUK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2159 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (N-Term) antibodyCHUK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the IKK alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the IKK alpha antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
- 别名
- IKK alpha (CHUK 产品)
- 别名
- ikk antibody, ikk1 antibody, ikka antibody, ikkalpha antibody, CHUK antibody, IKBKA antibody, IKK-alpha antibody, IKK1 antibody, IKKA antibody, NFKBIKA antibody, TCF16 antibody, AI256658 antibody, Chuk1 antibody, Fbx24 antibody, Fbxo24 antibody, Ikka antibody, zgc:56539 antibody, conserved helix-loop-helix ubiquitous kinase S homeolog antibody, conserved helix-loop-helix ubiquitous kinase antibody, chuk.S antibody, CHUK antibody, Chuk antibody, chuk antibody
- 背景
- Inhibitor of nuclear factor kappa-B kinase subunit alpha, also known as conserved helix-loop-helix ubiquitous kinase (CHUK) or IKBKA, is a protein kinase that in humans is encoded by the CHUK gene. It is mapped to 10q24.31. This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. IKK alpha is part of the IkB kinase complex that plays an important role in regulating the NF-kB transcription factor. IKK alpha also has many additional cellular targets, and is thought to function independently of the NF-kB pathway to regulate epidermal differentiation.
- 基因ID
- 1147
- 途径
- PI3K-Akt Signaling, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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